Senior Scientist - Target Discovery and Biology

Career Category - Scientific Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this. Let’s change the world. In this vital role you will join an enthusiastic, fast-paced team utilizing cutting-edge omics and cellular profiling technologies to advance target discovery, validation, and progression across Amgen’s therapeutic areas.

• Conduct impactful high throughput screening and profiling approaches for target discovery
• Help identify and implement new technologies to accelerate discovery
• Develop and execute downstream mechanistic assays to validate and advance targets
• Collaborate closely with disease area, human genetics, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert
• Present research findings to cross-functional groups at internal and external meetings and publish scientific findings in peer-reviewed forums

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a go-getter with these qualifications.

Doctorate degree PhD OR Pharm

D OR MD [and relevant post-doc where applicable]

Master’s degree and 3 years of directly related experience

Bachelor’s degree and 5 years of directly related experience

• Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines
• Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals
• Hands-on expertise conducting and delivering complex screening campaigns for discovery
• Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry
• Expertise with molecular and cell biology tools such as CRISPR, over-expression constructs, lentivirus, and various approaches for cell engineering
• Strong expertise with genomic assays
• Strong expertise on prosecuting insights from human genetics along with approaches for in depth biological study of potential targets
• Experience with programming (e.g. in R/Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets is preferred
• Strong written, verbal, and oral communication skills and ability to thrive in cross-functional settings

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards…