Senior Scientist - Target Discovery and Biology

Senior Scientist - Target Discovery and Biology

Join Amgen’s mission of serving patients. If you feel like part of something bigger, it is because you are. At Amgen, our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we have helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. As a member of the Amgen team, you will help make a lasting impact on the lives of patients by researching, manufacturing, and delivering innovative medicines.

• Conduct impactful high-throughput screening and profiling approaches for target discovery.
• Help identify and implement new technologies to accelerate discovery.
• Develop and execute downstream mechanistic assays to validate and advance targets.
• Collaborate closely with disease area, human genetics, computational biology, and therapeutic development teams to make actionable decisions as a technical and intellectual subject matter expert.
• Present research findings to cross‑functional groups at internal and external meetings and publish scientific findings in peer‑reviewed forums.

The dynamic professional we seek is a go‑getter with the following qualifications.

• Doctorate degree (PhD, Pharm
  
  D, or MD) and relevant post-doc experience where applicable.
• OR Master's degree with 3 years of directly related experience.
• OR Bachelor's degree with 5 years of directly related experience.

• Doctorate degree in genetics, genomics, cell and molecular biology, systems biology, or related disciplines.
• Demonstrated track record of independent critical thinking, complex problem solving, and innovative research, evidenced by significant contributions to discovery programs and publications in top tier journals.
• Hands‑on expertise conducting and delivering complex screening campaigns for discovery.
• Proficiency with experimental design, data generation, and analysis principles across a broad range of technologies and assays including transcriptomics, imaging, and cytometry.
• Expertise with molecular and cell biology tools such as CRISPR, over-expression constructs, lentivirus, and various approaches for cell engineering.
• Strong expertise with genomic assays.
• Strong expertise on prosecuting insights from human genetics along with approaches for in‑depth biological study of potential targets.
• Experience with programming (e.g., in R or Python), Unix/Linux environments, and cloud computing environments for the analysis of large omics datasets is preferred.
• Strong written, verbal, and oral communication skills and ability to thrive in cross‑functional settings.

We work to develop treatments that take care of others while caring for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a total rewards plan, comprising health and welfare plans for staff and eligible dependents, financial plans, work/life balance opportunities, and career development programs.

• A comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
• Stock‑based long‑term incentives.
• Award‑winning time‑off plans.
• Flexible work models, including remote and hybrid work arrangements where possible.

Apply now and make a lasting impact with the Amgen team.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.