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Full-Stack Engineer; Hybrid, South San Francisco

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: ESR Healthcare
Full Time position
Listed on 2026-01-11
Job specializations:
  • Software Development
    Full Stack Developer, Software Engineer
Salary/Wage Range or Industry Benchmark: 150000 - 190000 USD Yearly USD 150000.00 190000.00 YEAR
Job Description & How to Apply Below
Position: Full-Stack Engineer (Hybrid, South San Francisco)

Full-Stack Engineer (Hybrid, South San Francisco)
Who Are We? We are a fast-growing biotech startup revolutionizing DNA sequencing tools.

What's In It for You?
Build and Own Features: Work without product managers, directly shaping products used by thousands of scientists daily.
Competitive Compensation & Equity: $150,000 - $190,000 with meaningful equity.
Hybrid Work Model: Based in South San Francisco, working onsite three days per week (M/W/F), with a preference for five days per week.
Relocation Assistance: Available for strong candidates (estimated $5,000 - $10,000 relocation support).
Fast-Paced Startup Environment: Work on technically challenging projects that push the limits of speed, complexity, and innovation.

What Will You Do?
Develop customer-facing products end-to-end: Build impactful features without a product manager, working closely with designers.
Move quickly and deliver efficiently: Fix simple bugs on day one, ship small features within a week.
Tackle complex engineering challenges: Lead and execute high-impact, technically demanding projects.
Work across the stack: Develop and maintain scalable front-end and back-end systems using modern frameworks.

What Will You Need?
Required Experience:

• 5+ years in software development (7+ years required if no startup experience or CS degree).

• Full-Stack Expertise, ideally slightly front-end leaning.

• Early-stage startup experience:
Worked at a startup with fewer than 30 people (up to 100 considered).

• Lead-level product-minded engineer:
Can drive product development without oversight.

• Proficiency in Python (Django or Flask strongly preferred).

• JavaScript/Type Script experience, ideally React for front-end development.

• Strong SQL and relational database experience.

• Resume should demonstrate ownership of customer-facing products.

• Experience leading complex projects:
Not just maintenance, testing, internal tools, or porting work.

Tech Stack:

• Back-End:
Python (Django, Flask preferred)

• Front-End:
React preferred, but experience with Type Script, Svelte, Vue, Angular is acceptable

• Databases: SQL, Relational Databases

Preferred Experience (Nice to Have):

• Experience with data visualization, particularly D3.js.

• Personal/side technical projects that demonstrate innovation and creativity.

• Passion for mission-driven work in health, climate, or technology.

• Notable industry recognition:
Impressive Git Hub following, published technical books, or expert-level contributions.

• Past experience hiring/managing 5+ engineers, but prefers individual contributor coding role.

• BS, MS, or PhD in Computer Science (founders are PhDs from Cal Tech).

• Ranked university with a strong CS background and curiosity for biology-related tech.

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