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Research Scientist - Drug Discovery

Job in Vereeniging, 1904, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-26
Job specializations:
  • Research/Development
    Drug Discovery, Research Scientist, Pharmaceutical Science/ Research, Clinical Research
Job Description & How to Apply Below
Location: Vereeniging

About the Role

Our client is seeking a talented and driven Research Scientist to join their innovative Drug Discovery team in Vereeniging . This role is crucial for identifying and validating novel therapeutic targets and advancing lead compounds through the preclinical pipeline. You will work in a state-of-the-art laboratory, employing a range of biochemical and cellular assays to assess drug efficacy and safety. The ideal candidate possesses a strong background in pharmacology or a related field, with hands-on experience in assay development and compound screening.

This is an exciting opportunity to contribute to the development of life-saving medicines and advance your career in pharmaceutical R&D within our Vereeniging facility.

Key Responsibilities
  • Design, develop, and validate biochemical and cellular assays for target validation and drug screening.
  • Execute high-throughput screening (HTS) campaigns and analyze results to identify hit compounds.
  • Conduct dose-response studies, mechanism of action studies, and preliminary pharmacokinetic assessments.
  • Collaborate closely with medicinal chemists and pharmacologists to optimize lead compounds.
  • Prepare detailed experimental reports, present findings to project teams, and contribute to scientific publications.
  • Maintain laboratory equipment and ensure compliance with safety and regulatory standards.
Requirements
  • PhD in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
  • A minimum of 4 years of post-doctoral or industry experience in drug discovery research.
  • Proven expertise in assay development (biochemical and cell-based), compound screening, and data analysis.
  • Hands-on experience with relevant laboratory techniques such as enzyme kinetics, Western blotting, and reporter gene assays.
  • Strong understanding of target validation and preclinical drug development processes.
  • Excellent communication and teamwork skills.
Benefits
  • A competitive annual salary with performance bonuses.
  • Comprehensive health, dental, and vision insurance coverage.
  • Retirement savings plan and life insurance.
  • Generous support for professional development and scientific conferences.
  • Access to cutting-edge drug discovery technologies and facilities in Vereeniging .
  • A dynamic and collaborative work culture focused on innovation.
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