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Research Chemist - Organic Synthesis

Job in Mbombela, Mpumalanga, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-10-05
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Biotechnology, Pharmaceutical Science/ Research
Job Description & How to Apply Below
Location: Mbombela

Our client is seeking a talented Research Chemist with expertise in Organic Synthesis to join their dedicated R&D team in Nelspruit . This role is critical for the design, synthesis, and characterization of novel organic molecules for various applications, including pharmaceuticals and materials science. You will be responsible for planning and executing multi-step synthesis projects, troubleshooting synthetic challenges, and ensuring the high-quality production of target compounds.

This position offers a dynamic laboratory environment and the chance to contribute to innovative chemical research.

Key Responsibilities
  • Design and execute complex multi-step organic synthesis routes to prepare novel target molecules.
  • Purify and characterize synthesized compounds using techniques such as NMR, Mass Spectrometry, and HPLC.
  • Optimize reaction conditions to improve yield, purity, and scalability of synthetic processes.
  • Troubleshoot synthetic challenges and develop creative solutions to overcome obstacles.
  • Maintain detailed laboratory notebooks and prepare comprehensive reports on experimental results.
  • Collaborate with other chemists and researchers to support ongoing projects and initiatives.
Requirements
  • Ph.D. in Organic Chemistry or a closely related field.
  • Demonstrated expertise in modern organic synthesis methodologies and reaction mechanisms.
  • Hands-on experience with a wide range of synthetic techniques and purification methods.
  • Proficiency in spectroscopic characterization techniques (NMR, MS, IR, UV-Vis).
  • Familiarity with handling air-sensitive reagents and performing reactions under inert atmosphere.
  • Strong problem-solving skills and meticulous attention to detail.
Benefits
  • Competitive annual salary and performance-based bonuses.
  • Comprehensive health, dental, and vision insurance.
  • Retirement savings plan with employer contributions.
  • Paid time off and company holidays.
  • Opportunities for professional growth and development within the R&D department.
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