Research Scientist - Drug Metabolism and Pharmacokinetics; DMPK

Our client is seeking a dedicated Research Scientist with expertise in Drug Metabolism and Pharmacokinetics (DMPK) to join their R&D department in Nelspruit . This role is fundamental to understanding how drugs are absorbed, distributed, metabolized, and excreted by the body, which is critical for drug safety and efficacy. You will conduct in vitro and in vivo studies, analyze complex pharmacokinetic data, and collaborate with multidisciplinary teams to advance drug candidates through the development pipeline.

This is an exciting opportunity for a scientist eager to contribute to groundbreaking pharmaceutical research in Nelspruit .

• Design and execute in vitro DMPK studies (e.g., metabolic stability, CYP inhibition/induction).
• Plan and oversee in vivo pharmacokinetic studies in preclinical species.
• Analyze and interpret DMPK data using specialized software and statistical methods.
• Develop and validate bioanalytical methods for drug and metabolite quantification.
• Collaborate with medicinal chemists, toxicologists, and formulation scientists.
• Contribute to regulatory submission documents related to DMPK pharmacology.

• PhD or Master's degree in Pharmacology, Biochemistry, Pharmaceutical Sciences, or a related discipline.
• Minimum of 4 years of hands-on experience in DMPK research.
• Proficiency in conducting and interpreting various in vitro and in vivo DMPK assays.
• Experience with pharmacokinetic modeling and simulation software (e.g., Phoenix Win Nonlin).
• Strong understanding of drug development processes and regulatory requirements.
• Excellent scientific writing and communication skills.

• Competitive salary and comprehensive benefits package.
• Opportunities for professional growth and attending scientific conferences.
• Access to cutting-edge laboratory equipment and technologies.
• A collaborative research environment focused on innovation.
• Work in the scenic and accessible region of Nelspruit .