Senior Scientist

Join our high-performing Oligonucleotide Production team in Southampton—a vibrant coastal city offering the perfect balance of professional opportunity and quality of life, with excellent transport links.

We are seeking a Senior Scientist with deep expertise in downstream processing modalities including oligonucleotides/Peptides to lead analytical strategy and contribute to the development and production of high-quality modified Oligonucleotides

• Lead and oversee downstream workflows, supporting purification, analysis and characterisation of oligonucleotides including HPLC, SDS-PAGE, TFF and UPPL-MS
• Stay abreast of emerging technologies and methodologies in nucleic acid chemistry
• Drive method development and troubleshooting with purification techniques
• Ensure rigorous documentation
• Collaborate cross functionally across the organisation
• Coach and mentor junior team members

• PhDin Chemistry and/or related discipline
• Proven hands-on experience working with oligonucleotides/peptides is highly desirable within Academia or Industry (Small molecule experience will also be considered)
• Experience of UF/DF and TFF is highly desirable
• Strong background in purification and downstream processing techniques - HPLC, UPLC-MS, SDS-PAGE
• Experience working in ISO/GMP regulated environments is highly desirable
• Self-starter with the ability to lead projects which require troubleshooting and problem solving
• Detail orientated, strong communicator who can work under pressure in a fast-changing environment

• 25 days annual leave plus 8 paid bank holidays
• Contributory pension scheme (6% employer contribution)
• Flexible working hours
• Life Assurance (x4 salary)
• Long service awards
• Reward and recognition scheme
• Employer Assistance Programme with 24/7 remote GP service
• Annual flu jabs
• Cycle to work scheme
• Corporate discount on gym membership
• Savings and discounts
• Reimbursement of professional membership fees
• Referral incentives
• Social events
• Volunteering days

Biotage is a global supplier and solutions partner to a widerange of customers within drug discovery and development and analytical testing. With strong expertise in separation and purification technologies, and a focus on leveraging intelligent workflow solutions, we aim to efficiently support the advancement and protection of human health. Learnmore at