Life Science Research Professional

Life Science Research Professional 1 at Stanford University summary:

The Life Science Research Professional 1 at Stanford University conducts advanced genetic and molecular biology experiments to support research in cancer, neurodegeneration, and infectious diseases. Responsibilities include cell culture, CRISPR screening, sequencing, microscopy, data analysis, and lab management tasks such as ordering supplies and maintaining records. The role involves collaboration with senior researchers, ongoing literature review, and contributing to scientific publications to develop innovative therapeutics.

The Bassik Lab at Stanford University ( is seeking a Life Science Research Professional 1 to be an integral member of a research team that is developing novel genetic tools, including ultra complex CRISPR/Cas9 libraries, to conduct genetic screens in a range of medically relevant areas, such as cancer, neurodegeneration and infectious disease. The goal of this work is to understand (1) the biology of cancer development and identify novel therapeutic drug targets, as well as to (2) understand how macrophage cells of the immune system recognize and destroy pathogens ranging from protein aggregates to tumor cells.

Candidate must be willing to work in a research team, be organized, enjoy problem solving, and have strong communication skills. This is a fantastic opportunity for a motivated, creative, and reliable person to participate in highly collaborative, cutting-edge research at the forefront of modern biology, with real world applications to develop new therapeutics to improve human health.

Responsibilities include cell culture and maintenance of human cell lines, basic molecular biology (PCR, cloning, running DNA and protein gels), flow cytometry, preparation of samples for deep sequencing, confocal microscopy, basic statistical calculations, and other duties as assigned. The LSRP 1 will be expected to work closely with the PI to develop protocols, interpret and analyze the results of experiments, and suggest modifications to procedures as appropriate.

The position includes lab management tasks such as ordering supplies, maintaining lab records, and adhering to safety regulations. The LSRP 1 is expected to keep abreast of scientific literature and contribute new ideas and techniques to the lab, as well as attend lab meetings and journal clubs.

Duties include:

• Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
• Independently conduct experiments; maintain detailed records of experiments and outcomes.
• Primary experiments involve cell culture, molecular biology, high-throughput CRISPR screening, high-throughput sequencing and analysis
• Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
• Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
• Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
• Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
• Assist with orientation and training of new staff or students on lab procedures or techniques.

*- Other duties may also be assigned.

DESIRED

QUALIFICATIONS:

• Proficiency with basic molecular biology techniques, such as gel electrophoresis, PCR, and recombinant DNA techniques
• Experience with mammalian tissue culture techniques
• Meticulous record keeping and organizational skills
• Experience with high throughput sequencing methods and sample preparation, fluorescence microscopy, flow cytometry, lentivirus handling, and computer programming.

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor's degree in related scientific field.

KNOWLEDGE,

SKILLS AND ABILITIES

(REQUIRED):

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
• Ability to maintain detailed records of experiments and outcomes.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Ability to work under deadlines with general guidance.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

CERTIFICATIONS & LICENSES:

None.

PHYSICAL REQUIREMENTS*:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop,…