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Principal Machine Learning Engineer - Bioinformatics

Job in Stellenbosch, 7600, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-10-18
Job specializations:
  • IT/Tech
    Machine Learning/ ML Engineer, Data Scientist, AI Engineer (Applied/Software), Data Engineering
Job Description & How to Apply Below
About the Role

Our client is seeking a highly experienced and innovative Principal Machine Learning Engineer to lead their bioinformatics initiatives. This fully remote role is pivotal in advancing our client's capabilities in analyzing complex biological datasets to drive scientific discovery and therapeutic development. You will be responsible for designing, developing, and deploying sophisticated machine learning models, collaborating with a world-class team of bioinformaticians, data scientists, and biologists.

This is an exceptional opportunity to shape the future of data-driven biological research from anywhere in South Africa, working on challenging problems with significant impact.

Key Responsibilities
  • Lead the design, development, implementation, and deployment of advanced machine learning models for bioinformatics applications, including genomics, proteomics, and drug discovery.
  • Architect robust and scalable data pipelines for processing and analyzing large-scale biological datasets.
  • Collaborate with cross-functional teams to understand biological questions and translate them into machine learning problems.
  • Develop novel algorithms and techniques to address specific challenges in biological data analysis.
  • Evaluate and benchmark different ML models and approaches, ensuring optimal performance and accuracy.
  • Mentor junior engineers and scientists, fostering a culture of technical excellence and innovation.
  • Stay at the forefront of machine learning and bioinformatics research, identifying and applying new technologies.
  • Communicate complex technical concepts and results effectively to both technical and non-technical audiences.
  • Contribute to the strategic direction of the company's data science and machine learning efforts.
Requirements
  • PhD or Master's degree in Computer Science, Machine Learning, Statistics, Bioinformatics, or a related quantitative field.
  • Minimum of 8 years of experience in machine learning engineering, with a strong emphasis on bioinformatics or computational biology.
  • Proven track record of leading complex ML projects from conception to deployment.
  • Expertise in deep learning frameworks (e.g., Tensor Flow, PyTorch) and classical machine learning algorithms.
  • Proficiency in programming languages such as Python and associated libraries (e.g., scikit-learn, pandas, Num Py).
  • Experience with cloud computing platforms (AWS, GCP, Azure) and big data technologies (e.g., Spark).
  • Strong understanding of biological data types and analysis workflows (genomics, transcriptomics, etc.).
  • Excellent problem-solving, analytical, and critical thinking skills.
  • Exceptional communication and collaboration skills, with the ability to work effectively in a remote team.
  • Experience in scientific software development and MLOps is highly desirable.
Benefits

This principal-level, fully remote role offers a highly competitive salary, comprehensive health and retirement benefits, substantial equity options, and generous professional development allowances. Work from your preferred location in South Africa, contributing to world-class scientific research. Our client fosters a collaborative and intellectually stimulating virtual environment, promoting work-life balance and offering ample opportunities for career advancement and impact.

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