Principal Safety Scientist - SERM

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

Find out more:

Our approach to R&D We are looking for this role to be based in the UK, Poland or Brazil.

For candidates seeking to be located at our Stevenage site, this role will temporarily be based ever, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.Job Purpose Provides medical/scientific knowledge in the safety evaluation and risk management of GSK products in clinical development and/or the post-marketing setting.

Ensures scientifically sound review and interpretation of data and management of safety issues and escalates safety issues identified through the safety review process to senior management and safety governance as appropriate. Makes recommendations for the further characterization, management, and communication of safety risks.

Focus on efficiency and effectiveness to meet the needs of our Patients and HCPs.  Supporting the pharmacovigilance and benefit-risk management of the assigned portfolio of GSK global assets to ensure Patient Safety globally.

If appointed as a manager (i.e., Team/Group Leader) is responsible for leadership of a team of individual contributors.  Line Management (including functional matrix reports) leadership competencies include resource and team management, coaching, influencing others, collaborative working, decision making, change management, partnership, and relations  this role you will...Scientific/Medical Knowledge & PV Expertise Leads signal detection and evaluation activities for assigned products.

Produces clear, accurate, and fit-for-purpose safety evaluations in response to internal and regulatory requests.

Contributes to Risk Management Plans (RMPs), risk assessments, and safety documentation in collaboration with senior colleagues.

Authors and reviews global periodic safety reports, aggregate reports, protocols, and other regulatory documents within agreed timelines.

Participates in process improvement initiatives and ensures timely completion of audit and inspection follow-up activities.

Utilizes multiple data sources to investigate safety issues, propose solutions, and support decision-making in consultation with SERM physicians.

Effectively prioritizes workload, manages competing deadlines, and consistently delivers high-quality outputs with minimal supervision.
2. Cross-Functional Matrix Leadership Builds strong collaborative relationships across functions to address product safety matters.

Supports Safety Review Teams (SRTs) and governance activities in both development and post-marketing settings, helping to identify, evaluate, and mitigate safety risks.

Contributes to the implementation of risk minimization strategies in clinical protocols and product labeling.
3. Communication & Influencing Demonstrates strong verbal, written, and medical/scientific communication skills, producing high-quality evaluations and reports.

Supports and communicates safety risk positions clearly to internal and external stakeholders.

Why You?

Basic Qualification We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

- Degree in a health or life sciences discipline or healthcare professional qualification (for example, PharmD, PhD, RN, RPh, BSc) or equivalent experience.

- Experience in pharmacovigilance, safety evaluation, clinical safety or a related role in the pharmaceutical or biotech industry.

- Practical knowledge of safety evaluation methods, signal detection principles and adverse event reporting.

- Experience with clinical development and post-marketing safety activities.

- Good clinical and scientific literacy, including understanding of medical terminology and study design.

Preferred…