Principal Scientist

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

As a Principal Scientist you will lead scientific work that helps teams make faster, better decisions. You will design, validate and execute experiments that support both early and late clinical studies. You will work closely with project teams, laboratory colleagues and external partners. We value clear thinkers who share knowledge, care about quality, and enjoy mentoring others. This role offers strong opportunities to grow your technical and leadership skills while contributing to GSK’s mission of uniting science, technology and talent to get ahead of disease together.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Design, develop and validate robust spectral flow cytometry biomarker assays to support early and late clinical studies.
• Deliver, interpret and communicate complex scientific data to project/program teams within agreed timelines whilst managing multiple projects concurrently.
• Ensure high standards for data quality, record keeping and regulatory compliance in a GCP laboratory setting.
• Support assay transfers and collaborations with external partners and contract research organisations.
• Drive improvements in laboratory workflows, automation and data analysis to increase efficiency and reproducibility.
• Contribute to knowledge sharing across the organisation.

We are looking for professionals with these required skills to achieve our goals:

• MSc or equivalent practical experience in cell biology, immunology, biomedical science, pharmacology or related discipline with a significant computational component OR strong experience in Industry in a similar field having gained an undergraduate degree in one of the disciplines named above.
• Proven hands-on experience in flow cytometry.
• Demonstrable experience in assay development and optimisation of 18+ colour panels.
• Strong data analysis skills and clear written and verbal communication for scientific audiences.
• Experience working with human biological samples and understanding of relevant safety and ethical requirements.
• Ability to manage multiple projects, prioritise tasks and meet deadlines in a collaborative team environment.

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• PhD in a relevant scientific discipline.
• Practical experience with specific platforms such as the Cytek Aurora flow cytometer and OMIQ analysis software.
• Significant and demonstrable experience with computational approaches to high dimensional data analysis.
• Experience with both laboratory and analytical automation.
• Experience of assay validation, working within GCP or other regulated environments and familiarity with relevant regulatory expectations.
• Demonstrated ability to influence cross-functional teams and provide scientific leadership on projects.

Please take a copy of the Job Description, as this will not be available post closure of the advert.

Closing Date for Applications – 6th February 2026

When applying for this role, please use the ‘cover…