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Job Description & How to Apply Below
Title Graduate Student
Location Memorial University of Newfoundland, St. John's, NL
Summary The Oh Lab is seeking motivated and talented individuals to join our research group in the Department of Chemistry at Memorial University of Newfoundland. We are currently hiring two graduate students for exciting projects at the intersection of computational chemistry, molecular biophysics, and artificial intelligence.
Position 1:
Graduate Student Project
Title:
Developing Novel Therapeutics for Selective Inhibition of HIFP4H Isoenzymes
Project
Description:
This project focuses on building a graph neural network model that predicts the inhibitory activities of PHD2 inhibitors, and elucidating the molecular mechanisms of PHD2 inhibition using an integrative approach of machine learning, molecular dynamics, and molecular docking.
Qualifications:
Strong background in chemistry, biochemistry, biophysics, or a related field and keen interest in machine learning applications and interdisciplinary research.
Position 2:
Graduate Student Project
Title:
Deciphering the Molecular Basis of Retinoid and Non-retinoid Transport by RBPs
Project
Description:
This project involves machine learning-assisted collective variable discovery for enhanced sampling of retinol and lipid binding to RBP2 and RBP4 to understand the molecular basis of their affinities.
Qualifications:
Strong background in chemistry, biochemistry, biophysics, or a related field and keen interest in machine learning applications.
Qualifications Bachelor's or Master's degree in Chemistry, Biochemistry, Biophysics, Biology, or a related discipline.
Experience or knowledge with molecular dynamics simulations or machine learning is an asset but not necessary.
Strong analytical and problem-solving skills.
What You Will Learn Develop expertise in cutting-edge computational techniques.
Gain hands-on experience in collective variable discovery and enhanced sampling.
Acquire skills in computer-aided drug discovery and development of mathematical models.
Collaborate in a multidisciplinary environment.
Enhance proficiency in programming and data analysis.
Role Description This is a full-time graduate student role at Memorial University located in St. John's, NL. Responsibilities include engaging in research activities, attending seminars and workshops, collaborating with faculty members, participating in academic conferences, and contributing to teaching assistantships.
How to Apply
Interested candidates should send the following documents to Dr. Myongin Oh at
Cover letter detailing research interests, suitability for the position, and anticipated start date.
Curriculum Vitae (CV).
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