More jobs:
Head of Upstream Processing; USP
Job in
8954, Geroldswil, Kanton Zürich, Switzerland
Listed on 2026-06-11
Listing for:
evitria AG
Full Time
position Listed on 2026-06-11
Job specializations:
-
Research/Development
Biotechnology, Research Scientist
Job Description & How to Apply Below
Location: Geroldswil
We are seeking an experienced and hands‑on Head of Upstream Processing (USP) to lead upstream development activities for recombinant protein production in a dynamic biotech environment.
RESPONSIBILITIES- Lead and develop the USP team (scientists and technicians)
- Maintain a high level of training and scientific expertise within the team
- Mentor and support staff and actively support employee development
- Allocate and prioritize work within the team in alignment with the Head of Operations
- Provide scientific leadership in molecular biology, cell culture, and antibody expression
- Drive upstream process development for recombinant antibodies and complex antibody formats with excellent knowledge of cloning strategy, sequence design and DNA synthesis
- Establish scalable and robust USP workflows suitable for tech transfer and manufacturing
- Support business activities by proposing and reviewing USP‑specific components in customer quotations when required
- Continuously assess state‑of‑the‑art technologies and scientific developments
- Promote scientific excellence by identifying and initiating suitable development projects
- Ensure scientific standards, documentation quality, and compliance with internal procedures
- Define USP process steps, associated SOPs, and work instructions together with the team
- Lead the prevention and resolution of quality defects in production within the area of USP
- Ensure proper functionality, maintenance, and qualification status of equipment within USP
- Manage cross‑functional projects and coordinate activities across departments
- Collaborate closely with DSP and project management teams
- MSc or PhD in Biotechnology, Molecular Biology, or a related field
- Several years of industry experience in upstream processing of biologics, ideally antibodies
- Strong expertise in antibody formats and recombinant protein expression
- Deep knowledge of molecular biology techniques and mammalian cell culture systems
- Proven leadership experience managing scientific teams
- Hands‑on, pragmatic, and solution‑oriented mindset
- Strong communication and cross‑functional collaboration skills
- Experience in small biotech or startup environments is highly desirable
- Fluency in English and/or German
evitria is specialized in CHO‑based transient expression of antibodies (including bispecifics and fusion proteins). With a track record of more than 140,000 successful antibody production runs for our clients, we offer fast and reliable project execution at high quality standards.
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