Senior Manager, Safety Support Lead

• United States - Pennsylvania - Collegeville
• United States - New York - New York City

The Senior Manager, Safety Support Lead is responsible for end‑to‑end service delivery management of a defined application portfolio, ensuring performance, availability, quality, and financial stewardship. This role combines technical service ownership with people leadership, managing a team of Application Service Delivery Management (ASDMs) to deliver operational excellence and continuous improvement across the Safety portfolios in support of a global user base.

Will drive continuous improvement and innovation, leveraging automation and AI to enhance operational efficiency. Collaboration with infrastructure, platform, and business stakeholders is essential to maintain a stable, future‑ready application portfolio.

Must be able to work from the assigned Pfizer office 2–3 days per week, or as needed by the business.

Travel may be required as part of this role. Expectations around travel will vary but candidates must be capable of travel.

Pfizer Digital & Technology is a 7x24x365 endeavor. This role may require physical or virtual participation on a weekend, holiday, or after normal business hours.

The annual base salary for this position ranges from $135,100 to $225,100. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share‑based long‑term incentive program.

• Lead and develop team of ASDMs: oversee individual contributors, fostering a culture of excellence, collaboration, and continuous professional growth within the Enterprise Architecture and Support organization.
• Ensure application reliability and performance: maintain and optimize the portfolio of systems supporting the Regulatory and Medical business units, ensuring high availability and performance to meet critical business objectives.
• Seek opportunities for automation: promote the identification, design, and implementation of automation solutions, including traditional, self‑service, and GenAI capabilities to enhance operational efficiency and service quality.
• Manage financial stewardship: oversee budgeting, forecasting, and financial management activities to ensure responsible allocation of resources and achievement of financial targets.
• Partner for lifecycle management: collaborate with creation center teams and business stakeholders to recommend end‑of‑life upgrades and retirements.
• Support compliance and audits: ensure readiness for audits and inspections by maintaining robust controls over computer operations, access management, and change processes.

• Bachelor's degree in Information Management, Computer Science, Engineering, or Technology Management or a related field.
• Minimum 7+ years of progressive experience in information technology, including roles such as architect, business analyst, software developer, systems administrator, database administrator, systems engineer, support specialist, technology team lead, or manager.
• Experience and demonstrated competencies in working with teams in a matrixed organization, building strong relationships and driving successful cross‑functional outcomes.

• Experience managing systems supporting pharmaceutical operations or other highly regulated environments.
• Experience across multiple R&D domains including Research, Clinical, Safety, Regulatory, and Medical.
• Expertise in automation and AI‑driven solutions.
• Experience leading global or multi‑site teams.

Last Date to Apply for Job: 1/18/2026

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States.