Senior Manager, Safety Support Lead

We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.

• United States - Pennsylvania - Collegeville
• United States - New York - New York City

The Senior Manager, Safety Support Lead, is responsible for end-to-end service delivery management of a defined application portfolio, ensuring performance, availability, quality, and financial stewardship. This role combines technical service ownership with people leadership, managing a team of Application Service Delivery Management (ASDMs) to deliver operational excellence and continuous improvement across the Safety portfolios in support of a global user base.

Will drive continuous improvement and innovation, leveraging automation and AI to enhance operational efficiency. Collaboration with infrastructure, platform, and business stakeholders is essential to maintain a stable, future-ready application portfolio.

• Lead and develop team of ASDMs: Oversee individual contributors, fostering a culture of excellence, collaboration, and continuous professional growth within the Enterprise Architecture and Support organization.
• Ensure application reliability and performance: Maintain and optimize the portfolio of systems supporting the Regulatory and Medical business units, ensuring high availability and performance to meet critical business objectives.
• Seek opportunities for automation: Promote the identification, design, and implementation of automation solutions including traditional, self-service, and GenAI capabilities to enhance operational efficiency and service quality.
• Manage financial stewardship: Oversee budgeting, forecasting, and financial management activities to ensure responsible allocation of resources and achievement of financial targets.
• Partner for lifecycle management: Collaborate with creation center teams and business stakeholders to recommend end of life upgrades and retirements.
• Support compliance and audits: Ensure readiness for audits and inspections by maintaining robust controls over computer operations, access management, and change processes.

• Bachelor's degree in Information Management, Computer Science, Engineering, or Technology Management or a related field
• Minimum 7+ years of progressive experience in information technology, including roles such as architect, business analyst, software developer, systems administrator, database administrator, systems engineer, support specialist, technology team lead, or manager
• Experience and demonstrated competencies in working with teams in a matrixed organization, building strong relationships and driving successful cross‑functional outcomes

• Experience managing systems supporting pharmaceutical operations or other highly regulated environments
• Experience across multiple R&D domains including Research, Clinical, Safety, Regulatory, and Medical
• Expertise in automation and AI‑driven solutions
• Experience leading global or multi‑site teams

• Travel may be required as part of this role. Expectations around travel will vary but candidates must be capable of travel.
• Pfizer Digital & Technology is a 7x24x365 endeavor. This role may require physical or virtual participation on a weekend, holiday, or after normal business hours.

• Annual base salary: $ – $ (U.S. locations; Tampa, FL range $121,600 – $202,600)
• Global Performance Plan with a bonus target of 17.5% of the base salary
• Eligibility to participate in Pfizer’s share‑based long‑term incentive program
• 401(k) plan with Pfizer matching contributions and additional retirement savings contribution
• Paid vacation, holiday and personal days, paid caregiver/parental and medical leave
• Health benefits including medical, prescription drug, dental and vision coverage
• Relocation assistance may be available…