Cancer Immunology Postdoctoral Fellow

Overview

At Moffitt Cancer Center, we strive to be the leader in understanding the complexity of cancer and applying these insights to contribute to the prevention and cure of cancer. Our diverse team of over 9,000 is dedicated to serving our patients and creating a workspace where every individual is recognized and appreciated. Moffitt has been recognized on the 2023 Forbes list of America’s Best Large Employers and America’s Best Employers for Women, Computerworld magazine’s list of 100 Best Places to Work in Information Technology, Diversity Inc Top Hospitals & Health Systems, and named one of the Tampa Bay Time’s Top Workplace.

Moffitt is a National Cancer Institute-designated Comprehensive Cancer Center and a leading cancer hospital in Florida and the Southeast. We are a top 10 nationally ranked cancer center by Newsweek and have been nationally ranked by U.S. News & World Report since 1999. Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer.

Join our committed team and help shape the future we envision.

Cancer Immunology Postdoctoral Fellow –

The Beg laboratory is interested in developing new strategies aimed at modulating the tumor microenvironment to increase tumor immunogenicity and response to therapeutics. Through both laboratory and clinical trial studies, ongoing projects aim to modulate tumor T cell activity using both small molecule drugs and immune modulators. Specifically, the Beg laboratory is developing novel oncolytic virus strategies, now in clinical studies, to generate potent anti-tumor T cell responses.

Additional studies are focused on the immunological effects of KRAS pathway inhibitors towards the goal of increasing efficacy and attenuating resistance mechanisms.

• The researcher in this NIH-funded study will interface between the Beg lab in the Dept of Immunology and investigators in Moffitt’s Dept of Integrated Mathematical Oncology.
• A key component of the project will be to investigate the mechanism by which KRAS inhibitors impact the immune tumor microenvironment.
• The researcher will extensively utilize human specimens from biopsies collected in clinical trials, and resected tumors to perform spatial transcriptomic and mIF studies to define underlying mechanisms of action of KRAS inhibitors.
• Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.
• Outstanding mentorship from expert faculty with wide-ranging funded research programs including T32 Training Grants.
• You will be encouraged and supported to apply for training grants.

• Will have expertise in immunology and cancer biology.
• Be an independent thinker with desire for cross-disciplinary collaborations.

• Lead a project to define immunological impact of KRAS inhibitors in murine and human lung cancer.
• Collaborate with bioinformatics and mathematical oncology teams to provide insights into spatial impact of KRAS inhibitors and incorporate new methodologies and strategies.

• MD or PhD in a relevant field is required.
• Should have at least one first Author publication.

Moffitt Postdocs are provided with medical coverage and eligible for dental, vision, paid time off, retirement, parental leave and more. You may be eligible for relocation allowance per policy. Reasons to relocate include the Gulf Coast of Florida, Tampa being a thriving metropolitan city with a hub for groundbreaking research. This diverse city offers culture, beaches, cuisine and work/life balance.

If you have the vision, passion, and dedication to contribute to our mission,

then we have a place for you.