Principal Scientist, Precision Medicine Strategy Lead; Clinical Biomarkers

Position: Principal Scientist, Precision Medicine Strategy Lead (Clinical Biomarkers)
Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Precision Medicine Strategy Lead (Principal Scientist) to join our Translational Medicine organization, supporting clinical biomarker strategy for multiple clinical-stage assets across our Immunology & Inflammation, Ophthalmology, and Infectious Diseases portfolios. In this role, you will shape biomarker strategies that enable endpoint selection, indication choice, and demonstration of target engagement and mechanism of action, while collaborating with research teams, clinical development, laboratory operations, companion diagnostics, and external academic and alliance partners.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Location:

Tarrytown, NYWork model/flexibility: 4 days per week Discover your role:

Define and champion the strategic vision and scientific rationale for clinical biomarker plans across I&I, Ophthalmology, and/or Infectious Disease programs

Represent Precision Medicine on clinical development teams, driving biomarker strategy from concept through execution and interpretation

Partner with clinical and laboratory operations to implement biomarker and exploratory sample collection and analyses

Ensure clinical biomarker assays are fit-for-purpose, whether developed internally or through external collaborators and CROsPresent translational project plans, biomarker data, and results to internal and external stakeholders, including senior leadership

Contribute high-quality Precision Medicine content to clinical protocols, study reports, data reviews, biomarker reports, and manuscripts/publications

Translate complex immunology and disease biology into clear, testable biomarker hypotheses and decision criteria

Navigate ambiguity and prioritize across multiple programs in a collaborative, matrixed environment

This role requires:

Ph.D. with post-doctoral experience in Immunology or a closely related field highly desirable; 5+ years of relevant experience in pharmaceutical/biotech research and/or translational clinical development

Exceptional communication skills and strong emotional intelligence, with enthusiasm for presenting to senior leaders

Collaborative and innovative mindset, energized by working in a matrixed, cross-functional environment

Understanding of biomarker strategy in clinical development, including assay development, validation, and implementation

Preferred: track record of high-impact contributions to drug development programs

Preferred: experience authoring industry documents (protocols, CSRs, biomarker reports)
Alternative levels will be considered commensurate with experience.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family…