Principal Scientist, Formulation Development; DPDT

Position: Principal Scientist, Formulation Development (DPDT)
Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Scientist to join our Drug Product Development & Technology (DPDT) team. You'll lead drug product development activities from candidate selection and pre-clinical development through clinical development and commercialization for a variety of drug modalities, which may include protein (antibody), siRNA, peptides, bioconjugates (antibody-oligo or antibody-drug), and AAV, across a variety of drug and delivery presentations including liquid and lyophilized DP and novel drug delivery technologies.

You'll work independently to lead your project/program(s), applying biochemical, biophysical, and/or microbiology principles to execute both simple and complex experiments and processes.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Shift Requirements:
Full-time, standard business hours, with flexibility to support before- and after-hours executive meetings, town halls, and corporate events

Location:

On-site in Tarrytown, NY Discover your role:

Works independently and applies technical knowledge to design rigorous experiments that may include formulation, analytical, and process development and technology transfer

Acts as a resource and is recognized as a subject matter expert (SME) within their field; applies QbD approaches to drug product development and stays knowledgeable about current regulatory guidelines

Applies scientific and statistical knowledge of software packages (JMP or equivalent) to support study design and data analysis

Independently makes decisions of moderate complexity in a timely manner, including with limited information, understanding how decisions impact target priorities and cross-functional teams; uses a risk-based approach to make complex decisions and demonstrates judgment on when feedback from management is needed

Receives information and direction from leadership, and is responsible for planning and leading complex, long-term projects

Collaborates effectively as an SME and within cross-functional teams to support timely execution of deliverables

Proactively researches and implements new approaches toward problem-solving and/or process optimization for product development and new technology evaluations; capable of diving into novel fields and developing expertise needed in new areas or technologies

Brings managerial experience with demonstrated success developing direct reports; trains junior scientists in technical skills and mentors junior colleagues

Communicates effectively with varied audiences internally and externally, clearly explaining technical data that support recommendations or strategic direction

Participates in team meetings and prepares data presentations and documents, including publications and patents

Generates internal reports and authors external documents, which may include protocols, technical reports, risk assessments, regulatory documents, and patents

Maintains complete and accurate laboratory record documentation and complies with all data integrity procedures and system requirements, including ELN, SDMS, LIMS, and EDMSEngages in lab and instrument maintenance activities, acting as instrument SME or team lead, and may champion implementation of new instrumentation and analytical techniques

Complies with environmental, health, and safety requirements

This role requires:

A PhD in Pharmaceutical Sciences, Biochemistry, Chemistry, Biophysics, Biomedical or Chemical Engineering, or a related field with 4+ years of relevant industry experience in the biopharma space; or a BS/MS with a minimum of 10 years, of relevant industry experience

Industry experience with bioconjugates, particularly antibody-oligonucleotide formulation development, is preferred

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin,…