Principal Scientist, Biomarker & Drug Intelligence

** At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.
** We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day:  That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

** Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.
**** Position Summary
** The Principal Curation Scientist, Biomarker & Drug Intelligence, will serve as a pivotal member of the biomarker and drug intelligence team supporting the Caris Molecular Intelligence (CMI) knowledge base. This role involves working closely with the Vice President of the Biomarker & Drug Intelligence team and collaboratively across internal and cross-functional departments to update and maintain Caris precision-oncology products and services, including the Oncology Precision Medicine report which guides biomarker-driven treatment options for clinical use.

** Job Responsibilities
*** Lead strategic programs that continuously scan scientific, clinical-trial, and regulatory pipelines to surface high-impact biomarkers and drug candidates for precision-oncology products and services.
* Architect and govern enterprise-wide knowledge-management frameworks, setting best-practice standards for cataloging, harmonizing, and integrating multi-omic literature so downstream reporting and analytics remain current.
* Serve as a scientific spokesperson for designing and delivering high impact presentations and briefings that shape internal product strategy.
* Support the quality-management system for medical reporting, authoring and approving SOPs, monitoring key quality indicators, and partnering with Regulatory Affairs to ensure compliance.
* Support the vision and methodology for user-acceptance testing (UAT), by defining test architectures, success criteria, and automation roadmaps that guarantee scalable, fault-tolerant clinical-report updates.
* Direct cross-functional validation initiatives, unifying data scientists, software engineers, pathologists, and medical directors to stress-test releases and ensure every deliverable meets clinical, operational, and user-experience benchmarks.
* Champion organizational learning and external engagement, by mentoring scientists across disciplines, spearheading tumor-board and training curricula, and representing the company in consortia, standards bodies, and key scientific forums.
** Required Qualifications
*** Ph.D., M.D./Ph.D., or Pharm.

D. in a Biological Science related to Cancer Biology or Pharmaceutical Sciences.
* Minimum of seven years of industry experience in Biopharma, Biotechnology, or a related sector.
* The position requires the individual to live within the Phoenix, Arizona metropolitan area.
* Proven experience in curating literature using public databases, tools, and resources.
* Proficiency with Microsoft Office Suite (Excel, Word, PowerPoint), reference management tools (Endnote), virtual meeting platforms and information mapping/visualization software (e.g., Mind Manager).
** Preferred Qualifications
*** More than ten years of experience in the biotechnology and/or pharmaceutical industries is preferred.
* Strong foundation in Cancer Biology, Molecular and Cellular Biology, Genetics, or a related field relevant to precision medicine in oncology.
* Familiarity with precision medicine concepts and analytical platforms used to generate proteomic and genomic data for guiding patient therapy.
* Exceptional communication and presentation skills, with the ability to synthesize complex scientific information into clear, actionable insights for diverse audiences.
* Demonstrated ability to effectively communicate, coordinate, and…