Assoc. Director - Human Data & Computational Biology

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drides all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas
-Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Position:
Assoc. Director - Human Data & Computational Biology

Let’s do this. Let’s change the world. In this vital role you will help establish and lead the Human Data & Computational Biology capability within the Rare Disease Research Team. You will serve as a scientific partner across multiple disease areas, integrating human genetics, multi-omics, patient-derived data, and computational approaches to identify, prioritize, and validate novel therapeutic opportunities. We are seeking a scientist who combines deep computational expertise with strong biological intuition and a passion for understanding disease mechanisms.

Key Responsibilities

• Develop and implement computational strategies that support target discovery, validation, and prioritization.
• Analyze and interpret large-scale biological datasets, including genomic, transcriptomic, proteomic, imaging, and clinical data.
• Leverage human genetic evidence to strengthen disease understanding and therapeutic hypothesis generation.
• Collaborate closely with internal and external partners to integrate human genetics into early-stage discovery programs.
• Establish scalable analytical workflows and approaches that can be applied across multiple disease areas.

• Evaluate and implement emerging computational and AI-enabled approaches that accelerate scientific insight generation.
• Identify opportunities to integrate new technologies and analytical methods into the Rare Disease Research operating model.

• Work closely with disease biology pods to frame biological questions and translate computational findings into actionable scientific insights.
• Contribute to scientific evaluations of external opportunities, collaborations, and business development activities.
• Present scientific findings and recommendations to project teams, governance forums, and leadership groups.

• Establish processes and frameworks that promote human-data-driven decision making.
• As the function grows, participate in recruiting, developing, and leading future computational biology team members.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an Associate Director with the following qualifications:

Basic Qualifications

• Doctorate degree and 3 years of experience applying computational approaches to biological and translational research questions

OR

• Master’s degree and 7 years of analytics experience applying computational approaches to biological and translational research questions

OR

• Bachelor’s degree and 9 years of analytics experience applying computational approaches to biological and translational research…