LCMS​/MS Tech Specialist - BioPharma Services Inc.

Position Summary

Under the direction of the LC-MS/MS Team Leader, performs the set-up and conduct of analytical projects (validation and study) using LC-MS/MS equipment.

• Completes complex and highly specialized projects and bio studies related to LC-MS/MS analysis in APCI or Electrospray modes with positive and negative ion detection using multiple LC-MS/MS instruments and platforms.
• Conducts basic preventive maintenance and repair, troubleshooting of all LC-MS/MS instruments in the department to ensure smooth operations.
• Maintains strong knowledge and understanding of supporting instrument software and computer systems.
• Processes bioanalytical runs and completes applicable paperwork in a timely manner and provides to the production supervisor.
• Ensures the maintenance schedule for all LC-MS/MS instruments is followed.
• Coordinated repairs and service appointments with instrument vendor and/or third-party service technicians.
• Works independently, with broad latitude, in determining work activities to meet established objectives.
• Demonstrates excellent problem solving skills, solving complex and difficult problems where additional research is necessary; provides innovation to solve bioanalytical and instrument-related issues (Events and Quality Incident Reports).
• Provides advice, guidance and advanced level training to bioanalytical chemists.
• Maintains a sound knowledge of other laboratory equipment.
• Assists in developing and reviewing Standard Operating Procedures.
• Produces results and reports, in compliance with current applicable Standard Operating Procedures, for submissions to Canadian and International regulatory agencies.
• Demonstrates excellent written and oral communication skills.
• Provides information with some need for interpretation in dealing with external inquiries.
• Performs the job in a cost-effective and safe manner, complying with all relevant safety procedures and requirements.
• Performs the job according to approved Protocols and applicable GLP (OECD), EMEA, ICH, FDA and TPD requirements.
• Exhibits good interpersonal skills, a professional attitude and motivation to produce consistently high quality work.
• Performs other related duties assigned by the management.

• Generates analytical test results in compliance with all current SOPs, protocols, study plans and applicable GLP (OECD), EMA, ICH, FDA and TPD requirements.
• Documents and communicates any deviations to these instructions directly to the Principal Investigator (for GLP studies) or Study Director (for Non-GLP studies).
• Records raw data promptly and accurately and in compliance with the OECD Principles of Good Laboratory Practice.
• Exercises health precautions to minimise risk to him/herself and to ensure the integrity of the study; communicates to Laboratory Management any relevant known health or medical condition so he/she can be excluded from operations that may affect the study.

• BSc. or College Diploma in Analytical chemistry or related subject.
• Minimum of 3 years of related experience directly involved in the use and applications of LC-MS/MS system.