Postdoctoral Researcher

• Compensation: CAD 54902 - CAD 93333 - yearly

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care.

UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

• Union: Non-Union
• Number of Vacancies: 1
• New or Replacement Position: New
• Site: Princess Margaret Research Institute
• Department: Research
• Reports to: Scientist
• Salary Range: $54,902 - $93,333 Per Year
• Hours: 37.5 hours per week
• Shifts: Monday - Friday
• Status: Temporary Full-Time
• Closing Date: July 22, 2026 (extended)

Position Summary: The newly established laboratory at the Princess Margaret Cancer Centre is seeking a highly motivated and outstanding Postdoctoral Researcher to join our multidisciplinary research program. Our research focuses on developing novel cancer therapeutics and innovative molecular tools for biomedical research using advanced antibody engineering technologies. Projects will be dynamic and multidisciplinary, offering substantial opportunities for learning and intellectual growth.

The Postdoctoral Researcher will work closely with Dr. Hattori (PI) and the research team to design and execute experiments, interpret results, and contribute to scientific discussions that help shape the laboratory’s research program. The successful candidate will be expected to demonstrate high productivity and creativity, actively engage with the scientific literature, and contribute to scientific writing, including manuscripts and fellowship or grant applications.

This position offers a highly collaborative environment with strong support for professional development.

• Design, execute, troubleshoot, and interpret experiments in close coordination with the PI.
• Contribute original scientific ideas and propose experimental approaches informed by current literature and ongoing findings.
• Perform experiments using appropriate techniques, including biochemistry and molecular biology, depending on project needs.
• Maintain rigorous documentation of experimental procedures and results to ensure reproducibility and data integrity.
• Develop, optimize, and implement new experimental procedures and protocols.
• Recommend improvements to existing workflows and help integrate new techniques when appropriate.
• Stay current with relevant literature and emerging technologies.
• Contribute to scientific manuscripts by drafting text, preparing figures, and revising content in collaboration with the PI and co-authors.
• Apply for individual fellowships or scholarships and contribute to grant applications.
• Present research findings at laboratory meetings, institutional seminars, and national or international scientific conferences.
• Work collaboratively with laboratory members, institutional collaborators, and core facilities.
• Provide guidance and support to junior trainees, fostering a rigorous, collaborative, and collegial research environment.
• Maintain confidentiality and adhere to institutional policies on research integrity, biosafety, and ethical conduct.
• Participate in other duties as needed to support laboratory operations and the overall success of the research program.

• Awarded a PhD within the previous 5 years, or an MD or DDS within the previous 10 years in Biochemistry, Molecular Biology, Biophysics, Protein Engineering, Structural Biology, Chemical Biology, Immunology, or Biomedical Engineering.
• Demonstrated strong experience in recombinant DNA techniques, protein biochemistry and biophysics (including protein expression, purification, and…