Analytical Chemist

Reporting to the Advisor, ADME RLT, the contractor scientist, analytical chemistry will contribute to the characterization of new candidate medicines being developed as part of Lilly’s radioligand therapy discovery pipeline. This role will support laboratory activities to profile the distribution, metabolism, and clearance of experimental pharmaceuticals being tested in vivo and in vitro. The ideal candidate will have experience with high throughput sample preparation, liquid chromatography, and mass spectrometry, as well as handling anatomical and biological materials.

• Prepare samples from chemicals, mammalian cells, animal tissues, and excreta.
• Operate liquid chromatography and mass spectrometry instrumentation.
• Maintain and calibrate scientific instruments, including chromatography systems and mass spectrometers.
• Sustain laboratory operations by stocking consumables inventory and supporting chemical waste disposal.
• Convert raw scientific data into reports using standardized templates.
• Maintain a safe working environment for themselves and others through compliance with health and safety protocols and regulatory requirements governing the use of human tissue and hazardous chemicals.

• B.Sc. in chemistry, biochemistry, chemical biology, pharmacy, or a related discipline.
• Experience performing quantitative chemical analysis.
• Comfort handling anatomical samples and excreta.
• Working knowledge of Microsoft Office.
• Additional Preferences:
• 1-2 years of industry experience in high throughput sample preparation and analysis.
• 1-2 years of experience contributing to a high-performing team.
• Technical training and experience using liquid chromatography, mass spectrometry, and related instrumentation.
• Experience in data processing, data analysis, critical thinking, and production of publication-quality visuals and writing.
• Experience with in vivo pharmacology.
• Experience with GLP/GMP protocols.
• Understanding of drug properties and in vivo behavior (PK/PD, ADME, and principles of medicinal chemistry).
• Proficiency in virtual laboratory notebook software, such as Signals, and Benchling.

The physical demands of this job are consistent with a laboratory environment.

• Work environment is onsite downtown Toronto near College Street and University Avenue at the MaRS building.
• Wearing standard PPE in the lab is required.
• Must have use of full dexterity to perform routine benchwork in a laboratory setting.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

This position’s work environment is in a laboratory.

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