Postdoctoral Researcher Job Toronto area,Ontario Canada,Software Development

Company Description

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care.

UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

Job Description

Union: Non-Union
Number of Vacancies: 1
New or Replacement Position: New
Site: MaRS
Department: Structural Genomics Consortium
Reports to: Senior Scientist
Salary Range: $54,902 - $93,333 Per Year
Hours: Hours Per Week
Shifts: Monday - Friday;
Day Shifts
Status: Temporary Full-time (2-Year Contract)
Closing Date: June 19, 2026

Position Summary:
We seek a Data scientist to develop innovative machine learning (ML) and Artificial Intelligence (AI) methods to predict drug-like small molecules from large chemical screens based on the DNA Encoded Library (DEL) and Affinity Selection Mass Spectrometry (ASMS) technologies.

The candidate will be hosted by the Structural Genomics Consortium (), and labs. The candidate will be responsible for aggregating the existing and future drug screening data and developing novel integrative machine learning/AI models for the identification of potential drug targets; approved or experimental drugs.

The candidate will be assisted by software developers to leverage internal tools () in order to develop, train and test ML and DL predictive models, independently or in collaboration with other experts in the Haibe-Kains and Schapira labs and other SGC collaborators.

Duties:

Develop and implement novel ML/AI algorithms to predict drug-like small molecules from large-scale chemical screening datasets.

Utilize computational approaches to analyze complex drug screening data and extract meaningful insights.

Collaborate with computational biologists and software developers to build, validate predictions and deploy models on the platform.

Contribute to the design and execution of experiments to validate target predictions.

Stay abreast of the latest advancements in machine learning, AI, and chemical biology research.

Publish research findings in high-impact scientific journals and present results at conferences.

Qualifications

Awarded a PhD within the previous 5 years, or an MD or DDS within the previous 10 years, in computational chemistry, computer science, engineering, applied physics or equivalent.

Strong background in AI, deep learning, and machine learning.

Published/submitted papers in Scientific Journals or Conference Proceedings.

Experience with analysis of high-throughput drug screening data, such as DNA-Encoded Library (DEL) and/or Affinity Selection Mass Spectrometry (ASMS).

Strong data engineering skills.

Strong expertise in programming and machine learning (eg, PyTorch, Vertex

AI, Flask, Tensor Flow).

Excellent communication skills and ability to work effectively in a collaborative research environment.

Prior experience in computational chemistry or drug discovery research, preferred

Knowledge of cheminformatics, structural bioinformatics, or systems biology, preferred

Experience with high-performance computing and cloud computing platforms like Google Cloud Platform, preferred

Additional Information

Why join UHN?
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

Competitive offer packages

Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP )

Close access to Transit and UHN shuttle service

A flexible work environment

Opportunities for development and promotions within a large organization

Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

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