Operational Technology and Manufacturing Manager

This job is with GSK, an inclusive employer and a member of my Gwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients' needs and drive our performance.
Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it's vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.
We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

Job title:

Operational Technology and Manufacturing Manager
Location :
Rosia, Italy

Employment type:

Permanent
Closing date for applications:  30 August 2026
Position Summary
The    OT Security and System Architecture Manager     - OT Strategy, Resilience and Architecture    role is accountable for defining, governing, and continuously improving the  OT cybersecurity strategy, resilience framework, and target architecture  for the site. The role ensures that  OT systems are secure, resilient, compliant, and architecturally sound by design , GMP/GxP compliance, data integrity, and long‑term digital transformation objectives. Acting as the  architectural and security authority for OT , the role bridges  Automation, OT Operations, IT, Quality, and Global Cybersecurity , translating standards and threat landscapes into  practical, risk‑based, and sustainable OT architectures .
This is an individual contributor role  (no direct reports).
Responsibilities
OT Security Strategy:
Define and maintain the  Site OT Security and Strategy , aligned with Global OT Cybersecurity policies and Site Master Plan. Embed  security‑by‑design and resilience‑by‑design principles  into OT systems, networks, and execution platforms.
Identify and manage  cyber, operational, and architectural risks  impacting OT systems and manufacturing continuity.
Lead site‑level  OT risk assessments , threat modelling, and mitigation plans.

OT Architecture Governance   Define and govern the  Target OT Architecture  (zones, conduits, network segmentation, remote access, edge and execution layers).
Ensure consistency and compliance of OT solutions (PLC, SCADA, DCS, MES, LES, historians, data platforms) with approved OT architectures.
Review and approve OT architecture designs for:
New projects, Major changes, Technology refresh and obsolescence programs
Maintain architectural documentation (OT LDD, HLD, reference architectures).

Lifecycle, Obsolescence & Technology Evolution   Drive secure OT lifecycle management, from design to decommissioning.
Support OT obsolescence management plans ensuring security, resilience, and compliance are preserved.
Evaluate emerging OT security and architecture technologies, supporting informed investment decisions.

Governance, Compliance & Stakeholder Engagement   Ensure OT architectures meet GMP/GxP, Data Integrity (ALCOA+), CSV and cybersecurity requirements.
SPOC for Business continuity delivering look ahead systems/services down time plan
Act as Subject Matter Expert (SME) for OT security and architecture during audits and inspections.

Partner with Automation, Digital, Quality, IT, MSAT, and Global functions to align priorities and execution.
Promote OT security awareness and architectural discipline across the site.

Why you?

Qualifications & Skills
We are looking for professionals with these required skills to achieve our goals:
Master's degree  in Engineering (Automation, IT, Electronics, Industrial, or equivalent).

At least 10 years of experience in similar roles in Pharma companies.

Proven leadership experience in Automation, Digital, or OT roles within complex and regulated industrial…