Research Fellow in Biochemistry & Biomedicine

Research Fellow in Biochemistry & Biomedicine  (Fixed Term) Location

Brighton, UK

Full-time considered up to a maximum of 1.0 FTE (37.5 hours) Requests for flexible working options will be considered (subject to business need). Candidates would be expected to be in for core hours where meetings or seminars are typically scheduled (e.g. ).

Grade 7 starting at £38,784 to £46,049 per annum, pro rata if part time.

Fixed Term Contract

Dr Rhys Morgan’s research group is seeking to appoint a highly talented and motivated Research Fellow to lead a 3-year Cancer Research UK funded project titled ‘Detecting and targeting translation inhibitor sensitive RUNX1 mutations in chronic myeloid leukaemia’. You will work independently to produce high quality experimental data in the laboratories of the Biochemistry & Biomedicine department, which will be used to write scientific publications, obtain further research funding, be presented at internal seminars, and submitted to national/international conferences.

You will be required to supervise project students and contribute to wider school missions around teaching, public engagement and research culture.

You will benefit from the supervision and mentorship of a new scientific/clinical partnership between Dr Morgan (School of Life Sciences) and Dr David Palmer (University Hospitals Sussex NHS Trust) and be part of the wider Sussex Blood Cancer Research network with colleagues in Brighton & Sussex Medical School.

You will benefit from interactions with the Sussex RNA Biology Centre and be embedded within the Sussex Cancer Research Centre, which unites all cancer researchers across Sussex.

This will be a laboratory-based project favouring those with practical experience in a variety of cellular (myeloid cell line, patient sample and stem cell culture), genetic (RNAi, CRISPR/Cas9 and transfection/transduction) and molecular (flow cytometry, immunoblotting, RT-qPCR, RNA immunoprecipitation) techniques across in vitro and in vivo models. You should be computationally literate and competent with basic bioinformatic analyses. You will be flexible to attend extended visits to collaborators at the Universities of Glasgow and Nottingham to complete experimental work during the study.

You should be highly motivated, and ambitious, looking to pioneer new approaches where required and demonstrate resilience to overcome experimental challenges. You will have the ability to multi-task and run multiple experiments in parallel. You will be well organised and able to work effectively as part of a collegiate team to manage the laboratory and assist other researchers in working on related projects.

You’ll report punctually and reliably at regular progress meetings and be to communicate effectively with laboratory scientists, clinicians, and non-expert audiences.

In the School of Life Sciences, we strive to understand the mechanisms that drive biological and chemical processes and to develop innovative and diverse approaches to enhance human health, technology and the environment. We undertake multidisciplinary research, teaching and engagement across a wide range of subjects, from Chemistry through Cellular and Molecular Biosciences to Conservation Biology.

The School comprises five Departments:
Biochemistry & Biomedicine, Genome Damage and Stability Centre, Neuroscience, Ecology & Evolution and Chemistry. We also house the Sussex Drug Discovery Centre which works to deliver the bench-to-bedside translation of our discoveries. The breadth and depth of our cutting‑edge research and innovative teaching practice is delivered by a diverse community who work across boundaries to deliver excellence, engage with real world problems and produce impact.

We pride ourselves on our world‑leading research and have a strong research economy, with approximately 50% of our income stemming from research and an active grant portfolio of over £50 million. We host or form part of three University Centres of Excellence : the Genome Damage and Stability Centre, Sussex Neuroscience and Sussex Sustainability Research Programme. In the 2021 Research…