Clinical Research Manager

The Clinical Research Manager will play a key role in advancing ARUK’s drug prioritisation activities as part of the Clinical Accelerator Programme. Working closely with the Senior Clinical Research Manager, this role will drive the identification, evaluation, and progression of high‑potential drug candidates toward clinical trials, delivering tangible impact for people affected by dementia.

This role is vital in advancing Alzheimer’s Research UK’s research objectives and organisational strategy and will be key to delivering impact for people affected by dementia. The Clinical Research Manager will manage the planning and delivery of ARUK’s drug prioritisation activities working collaboratively with external stakeholders and various departments across the organisation, including the wider Research, Fundraising and Policy, Communications and Involvement Teams to develop the programme and ensure successful delivery and measurable impact.

This role sits within the Clinical Research team in the Research Directorate, an ambitious, proactive and growing team that is driving forward initiatives to bring more clinical trials to the UK for people living with or likely to develop dementia. With the first generation of disease‑modifying treatments recently approved, this is an exceptional opportunity for an individual with strong research experience who understands the clinical research environment in the UK, to contribute to ground‑breaking work in dementia research, aligning with and advancing on the Government’s new investment initiatives in the Dame Barbara Windsor Dementia Goals.

• Lead on the identification of therapies with the potential to be prioritised for clinical trials in Alzheimer’s and other types of dementia through literature search and communication with the clinical research community and key external partners, with support from the Senior Clinical Research Manager.
• Lead the development and drafting of high‑quality scientific dossiers that directly inform prioritisation decisions and progression of drug candidates.
• Lead the translation of recommendations from external advisory panels into actionable next steps.
• Work with the Senior Clinical Research Manager and the Senior Clinical Programmes Operations Officer to plan drug prioritisation activities, including meeting logistics, panel engagement, feedback and to track and evaluate progress.
• Identify, evaluate, and drive forward high‑impact opportunities for drug prioritisation and clinical development in consultation with Partnerships, Evidence and Funding teams.
• Design and embed scalable processes to proactively monitor the global drug development landscape, utilising databases, conference intelligence, and literature to curate a dynamic intelligence log that tracks therapeutic candidates, development progress, and emerging opportunities across industry and academia.

• Drive planning and implementation of new activities as relevant to continually develop and advance the clinical research strategy.
• Collaborate in mapping the clinical research ecosystem, identifying gaps in research and recommending actions to address them.
• Keep abreast of developments and trends in dementia clinical research to influence ARUK’s strategies and decisions.
• Support and continuously strengthen internal reporting mechanisms, ensuring timely, high‑quality updates to Senior Leadership and relevant boards that enable effective governance, informed decision‑making, and strong organisational coordination.
• Work closely with the Research Involvement Manager to integrate best practices in involvement and co‑production to ensure our research is relevant for and supported by people affected by dementia.
• Ensure effective information‑sharing across internal stakeholders, including Research, Fundraising, Finance, Policy, Communications and Involvement teams, to maximise the visibility, uptake and strategic use of Clinical Accelerator Programme outputs.
• Aid in the planning, production, and communication of clinical research‑related content with the ARUK…