Senior Scientist - Toxicology

We are looking for an experienced Senior Scientist to help drive the development of future Toxicology capabilities at Cyprotex.

Are you passionate about assay development, scientific innovation, and external collaboration? Do you enjoy solving complex scientific challenges and working at the forefront of emerging technologies? If so, we’d love to hear from you.

Role: Senior Scientist

Role Type: Permanent

Hours: Full time, 37.5 hours per week

Salary: Competitive salary plus excellent company benefits

Location: Alderley Park, Macclesfield, SK10 4TG

Cyprotex, part of the Evotec Group, is a leading provider of in vitro and in silico ADME-Tox services supporting discovery and development programmes globally.

As our business continues to expand, we are investing in new scientific capabilities and innovative technologies. We are therefore seeking a Senior Scientist who will help drive scientific excellence, assay development, external collaborations, and capability growth within our Toxicology group.

As our Senior Scientist, you will combine hands‑on laboratory delivery with responsibility for scientific development, assay improvement and technical leadership within the Toxicology group.

A substantial proportion of the role will remain focused on routine client work, whilst also providing opportunities to contribute to scientific innovation and capability development.

• Running high‑and‑low‑throughput in vitro toxicology assays for commercial and research projects.
• Performing routine cell culture activities using a range of cellular models and assay systems.
• Generating, analysing and interpreting high‑quality scientific data for client studies.
• Supporting delivery of routine and complex client projects to agreed timelines and quality standards.
• Acting as a technical lead for designated assays, technologies or scientific platforms.
• Providing troubleshooting support for complex scientific challenges.
• Supporting assay development, optimisation and validation activities.
• Designing and conducting feasibility and proof‑of‑concept studies.
• Evaluating new technologies, methodologies and scientific approaches.
• Supporting implementation of innovative workflows that improve scientific capability and client value.
• Working closely with Information Systems and Automation to improve processes and data handling.
• Contributing scientific expertise to client discussions, proposals and technical meetings.
• Supporting the preparation of scientific posters, presentations and publications.
• Coaching and mentoring colleagues undertaking scientific development projects.
• Maintaining awareness of emerging scientific advances and regulatory developments within in‑vitro toxicology.

• BSc, MSc, PhD or equivalent industrial experience in a Life Sciences discipline.
• Significant experience within a CRO, pharmaceutical, biotechnology or research environment.
• Strong practical experience in cell culture and in vitro toxicology assays.
• Expertise in assay troubleshooting, optimisation and scientific problem‑solving.
• Experience supporting assay development or research projects.
• Strong experimental design and data analysis skills.
• Excellent written and verbal communication skills.
• Ability to collaborate effectively across multidisciplinary teams.
• Passion for scientific innovation and continuous improvement.

• Experience in High Content Imaging (HCI), High Content Screening (HCS), flow cytometry, Seahorse or advanced cell‑based assays.
• Experience presenting scientific work internally or externally.
• Publication record within a relevant scientific field.
• Experience implementing new technologies or laboratory workflows.
• Experience supporting…