Who We Are
Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team.
What We DoWe are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026.
Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial.
In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN
1701 and XEN
1720 (targeting Nav
1.7) and XEN
1120 (targeting Kv7), which are being developed for pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.
The Role
We are seeking a Clinical Trial Associate 1 or 2 to join our team. The Clinical Trial Associate 1 or 2 will be an individual responsible for supporting Clinical Operations team members with project-specific support related to the conduct of clinical trials activities. The Clinical Trial Associate 1 or 2 will assist the clinical research teams in ensuring the most effective and efficient conduct of clinical research studies by providing administrative and project tracking support.
This position reports to the Director, Trial Operations, and will be based out of our Vancouver, BC office. The level of the position will be commensurate with the candidate’s education and industry experience. This is a Hybrid position requiring a minimum of two onsite days per week.
- Work with the clinical operations team in review of clinical documents (Protocols, Informed Consents, study plans and related documents). Participate in study start up activities including preparation and maintenance of study reference manuals, site tools, templates, source documents and guidelines.
- Assist with the review and tracking of key regulatory documents required for site activation, including the tracking and review of site/country specific informed consent forms.
- Develop and regularly update clinical trial tracking tools and systems that provide metrics and tracking of a clinical trial’s progress, including patient recruitment, trial supplies and trial documentation.
- Support the study specific trial master file by filing and maintaining electronic trial master file (eTMF) for sponsor documents, review of eTMF plans and perform quality oversight of CRO eTMF throughout trial.
- Collaborate with CROs, vendors…
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