Research Scientist – Protein Mass Spectrometry Job Vancouver area,BC Canada,Research/Development

Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.

We are looking for a highly motivated scientist with demonstrated hands-on experience using mass spectrometry and other analytical techniques to join our team. You will focus on the characterization of antibodies and/or other therapeutic proteins, while working in a fast-paced, collaborative environment, interacting with a diverse team of scientists.

How you might spend your days

Developing, designing, and qualifying LC-MS methods for qualitative and quantitative analysis of antibodies, other proteins, and/or small molecules

Performing detailed protein structural interrogation, including sequence confirmation, sequence variant identification, disulfide mapping, or chemical modifications in support of batch comparison, forced degradation and developability analysis

Developing and performing analytical assays for protein characterization such as ultra high performance liquid chromatography (UHPLC), light scattering (SEC-MALS, DLS), capillary electrophoresis (CE-SDS), or imaged capillary isoelectric focusing (icIEF)

Training and mentoring members of our team

Liaising with partners and communicating project updates and deliverables

Developing and implementing standard operating procedures

Organizing, supporting, and collaborating with team members to meet project deliverables and timelines

We'd love to hear from you if

You have hands-on experience with protein-focused high resolution mass spectrometry, including intact mass analysis, peptide mapping, and PTM analysis, glycan mapping, disulfide mapping, cross-linking MS, HDX-MS, or other related methods would be an asset

You have hands on experience with small molecule mass spectrometry, including absolute quantitation, structural elucidation, or other ADC-related small molecule MS techniques

You are able to implement methods for high throughput sample preparation and automated data analysis, and have experience in method qualifications and drafting SOPs

You have a PhD in Analytical Chemistry, Biochemistry, or a related field, or a have a MSc with 5+ years of relevant wet lab experience in an academic or industry setting

You have experience with, or an interest in working with, other analytical techniques such as UHPLC, CE-SDS, SEC-MALLS, DLS, or icIEF

You think critically, are curious, and want to explore new technologies and opportunities to improve antibody characterization workflows and processes

You are a creative problem solver and fast learner who believes in team work to tackle the most challenging scientific problems

You have great interpersonal skills, and thrive in a collaborative working environment as a member of cross-functional team

You have excellent documentation, organizational, and communication skills, impeccable attention to detail, and an ability to analyse and interpret large datasets

What we offer

AbCellera’s hiring range for this role is CAD $75,800 - $94,700 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

About Ab Cellera

Creating medicines is the most important work we can do.

We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline.

Today, our pipeline includes two drug candidates in clinical development, two preclinical…


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