Program Manager - Technical Operations

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis
* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.

For more information, visit , and follow the company on Linked In, X, Facebook and You Tube. (
* in collaboration with Abb Vie)

At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what’s ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

The Program Manager, Technical Operations supports the planning, execution, and operational effectiveness of Technical Operations programs across the development portfolio. The role provides program management leadership for complex, multidisciplinary initiatives and serves as a key operational partner to CMC functional leaders, program teams, and cross-functional stakeholders.

The Program Manager is responsible for translating program objectives into integrated execution plans, establishing effective governance, and operating rhythms, identifying and managing dependencies and risks, and ensuring transparency and accountability across participating functions. The role may coordinate six or more technical sub-teams or work streams within the scope of an assigned program and ensures that strategy, critical-path activities, interdependencies, decisions, and emerging risks are clearly communicated to appropriate stakeholders.

This position requires a strong understanding of pharmaceutical development and the interactions among core CMC disciplines, including Drug Substance/API Development, Analytical Development, Drug Product/Pharmaceutical Development, Manufacturing, Supply Chain, Quality, and CMC Regulatory. The Manager works cross-functionally with partners in Research, Clinical Development, Regulatory Affairs, Quality, Finance, and other functions to ensure Technical Operations activities support broader program and company objectives.

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Program and Project Management

• Lead the integrated planning and execution of assigned Technical Operations and CMC programs, initiatives, and major work streams from development planning through key program milestones
• Develop, maintain, and communicate integrated program plans, timelines, milestones, critical paths, dependencies, decision points, and key deliverables
• Establish and manage appropriate meeting cadences, governance forums, decision logs, action trackers, and status reporting mechanisms
• Monitor execution against agreed plans and proactively identify schedule risks, resource constraints, cross-functional dependencies, and emerging issues
• Partner with functional…