Associate Manufacturing Scientist ; 2nd shift

Associate Manufacturing Scientist I (2nd shift)

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a clinical-stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.

Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Associate Manufacturing Scientist I (second shift) will assist in the synthesis and subsequent purification steps of large scale oligonucleotides. 2nd shift work hours are 1pm – 11:30pm and includes a 10% shift differential.

• Follow batch records, SOPs, and work instructions to detail
• Document all operations in batch records and notebooks
• Comply with GMP protocols
• Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides including reagent solution preparation
• Reagent solution preparation
• Column Packing
• Fraction collection
• Operate a lyophilizer and package solid drug substance
• Execute processes as part of a team to ensure production timelines are kept and quality product is produced
• Maintain a clean work space
• Maintain safety by wearing required personal protective equipment

• Bachelor's degree in chemistry, biochemistry, engineering, or related scientific field
• Experience working in a GMP setting and controlled documentation
• Good verbal and written communication skills
• Ability to work in a team environment
• Ability to pay attention to detail Benefits

  Arrowhead provides competitive salaries and an excellent benefit package.

  Application Note

  All applicants must have authorization to work in the US for a company.