Senior Director, FP&A

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera isleveragingits proprietary switch-control kinase inhibitor platform and deepexpertisein kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’splatform in clinical studies, QINLOCK® (ripretinib) is Deciphera’sswitch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib.

ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatictenosynovialgiant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.

The spirit of collaboration that has brought medications to life continues to guide how weoperate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together.

Deciphera offers competitive compensation, including equity-based compensation,and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, lifeinsuranceand a flexible spending account for either health care and/or dependent care.

The Senior Director, Financial Planning & Analysis (FP&A) will lead Deciphera’s FP&A function and serve as a key strategic and financial partner to executive leadership, functional leaders, and Ono Pharmaceutical’s corporate headquarters in Japan. This highly visible role is responsible for leading company-wide budgeting, forecasting, and long-range financial planning while ensuring alignment between Deciphera’s business priorities and the broader Ono Pharma Group strategy.

The Senior Director will provide strategic financial leadership and analysis to support portfolio planning, investment decisions, and enterprise-wide resource allocation. Working closely with leaders across Deciphera and Ono Pharma headquarters, this individual will deliver financial insights, challenge key business assumptions, and help drive informed decision-making in support of both short- and long-term corporate objectives. In addition, the role will lead and develop a high-performing FP&A team while advancing the company’s financial planning, reporting, and decision-support capabilities to support continued growth and organizational success.

What You'll Do

• Lead the company's annual budget and quarterly forecasting processes, establishing financial targets, key assumptions, and planning timelines.
• Drive analysis of financial and operational performance against budget and forecast, identifying key drivers, risks, opportunities, and recommendations.
• Partner with functional leaders throughout the organization to provide financial guidance, challenge assumptions, and support informed decision-making.
• Lead financial reporting and forecasting activities in collaboration with Ono Pharmaceutical corporate headquarters.
• Develop impactful financial analyses, business cases, and executive-level presentations for senior leadership and global stakeholders.
• Ensure alignment…