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Senior Microsoft 365 Platform Engineer

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Repligen Corporation
Full Time position
Listed on 2026-11-04
Job specializations:
  • IT/Tech
    M365, SharePoint & Power Platform, Cybersecurity, Cloud Computing: Infrastructure & Operations, Systems Administrator
Salary/Wage Range or Industry Benchmark: 140000 - 180000 USD Yearly USD 140000.00 180000.00 YEAR
Job Description & How to Apply Below
Senior Microsoft 365 Platform Engineer# Careers## Senior Microsoft 365 Platform Engineer Apply:
Waltham, MA:
Full time:
Posted Today:
R-947A a highly skilled Senior Microsoft 365 Platform Engineer to lead the engineering, administration, governance, security, and continuous improvement of our global Microsoft 365 platform. This role will serve as the technical lead for Microsoft 365 collaboration, SharePoint Online, Identity & Access Management (IAM), Entra , and endpoint management services, ensuring secure, scalable, and reliable digital workplace solutions across the enterprise.
** Key Responsibilities
*** Own the administration, support, governance, and continuous improvement of Microsoft 365 services, including SharePoint Online, Teams, Exchange Online, One Drive, Entra , and Intune.
* Serve as the Tier 3 escalation point and technical authority for Microsoft 365 platform issues and initiatives.
* Design and implement secure, scalable M365 solutions aligned with enterprise architecture and security standards.
* Lead SharePoint governance, permissions management, site lifecycle management, collaboration standards, and migration initiatives.
* Administer and enhance Identity & Access Management (IAM) capabilities including Hybrid Identity, Single Sign-On (SSO), Multi-Factor Authentication (MFA), Conditional Access, Privileged Identity Management (PIM), and Identity Governance.
* Support enterprise application integrations using SAML, OAuth, OpenID Connect, and SCIM.
* Manage endpoint solutions through Microsoft Intune and Windows Autopilot, including device provisioning, compliance, application deployment, and endpoint security.
* Develop automation and operational improvements using Power Shell and Microsoft Graph.
* Monitor platform health, performance, security posture, adoption, and compliance metrics.
* Partner with Cybersecurity teams to implement Microsoft 365 security, compliance, and governance controls.
* Participate in incident response, root cause analysis, and continuous service improvement activities.
* Create and maintain architecture documentation, standards, runbooks, and operational procedures.
* Evaluate Microsoft roadmap enhancements and lead the adoption of new technologies and platform capabilities
** Qualifications
* ** Bachelor's degree in Information Technology, Computer Science, or related field, or equivalent experience.
* 7+ years of hands-on Microsoft 365 administration and engineering experience in a medium-to-large enterprise.
* Deep expertise in:  + Microsoft 365 Administration  + SharePoint Online Administration & Governance  + Microsoft Teams  + Exchange Online  + One Drive for Business  + Microsoft Entra  (Azure AD)  + Identity & Access Management (IAM)  + Microsoft Intune
* Strong experience with Hybrid Active Directory and Entra .
* Expertise implementing and managing SSO, MFA, Conditional Access, RBAC, PIM, and Identity Governance.
* Strong Power Shell scripting and Microsoft Graph automation experience.
* Experience supporting endpoint management, Windows Autopilot, and modern device management.
* Strong understanding of Microsoft 365 security, compliance, governance, and collaboration technologies.
* Experience with Microsoft Defender, Purview, Service Now, and ITIL processes preferred.
* Experience supporting global organizations and geographically distributed teams.
** Preferred Certifications
*** Microsoft 365 Certified:
Enterprise Administrator Expert (MS-102)
* Microsoft Certified:
Identity and Access Administrator Associate (SC-300)
* Microsoft Certified:
Endpoint Administrator Associate (MD-102)
* Microsoft Certified:
Cybersecurity Architect Expert (SC-100)
* Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated salary range for this role, based in the United States of America is $140,000-$180,000. Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data.

Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and…
Position Requirements
10+ Years work experience
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