Director, Marketing Operations

Overview

Cogent Biosciences is a publicly traded biotechnology company dedicated to developing precision therapies for genetically defined diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease and offer meaningful hope to patients.

The company’s lead therapeutic candidate, bezuclastinib, is a highly selective tyrosine kinase inhibitor designed to potently target KIT D816V and other mutations in KIT exon 17. These mutations are known drivers of systemic mastocytosis (SM) and advanced gastrointestinal stromal tumors (GIST) - both serious conditions driven by oncogenic KIT signaling. Bezuclastinib is currently being evaluated in multiple registration-directed trials across Non-Advanced SM (NonAdvSM), Advanced SM (AdvSM), and GIST.

In July 2025, Cogent announced that its registration-direct SUMMIT trial in patients with NonAdvSM achieved statistical significance across all primary and key secondary endpoints, and the company is on track to file its first New Drug Application for this patient population by the end of 2025. The company also remains on track to announce top-line results for its APEX trial in patients with AdvSM in the second half of 2025 and for its PEAK trial in patients with GIST by the end of 2025.

The company also has an ongoing Phase 1 study of its novel internally discovered FGFR2 inhibitor, and the Cogent Research Team is developing a portfolio of novel targeted therapies to help patients fighting other serious, genetically driven diseases targeting mutations in ErbB2, PI3Kα and KRAS.

Through its commitment to precision medicine and targeted innovation, Cogent Biosciences is working to transform the treatment landscape for patients with serious and underserved diseases. By leveraging validated biology and a rational drug discovery approach, Cogent aims to create real solutions that address the underlying drivers of disease. Our culture of inquisitiveness fuels continuous learning and innovation; we challenge assumptions, ask bold questions, and embrace a mindset of discovery to uncover transformative insights.

This critical role will lead the strategic and tactical execution of marketing operations supporting the launch of bezuclastinib, Cogent Biosciences’ key pipeline asset. This role ensures compliant, efficient, and impactful delivery of promotional content, omnichannel campaigns, key marketing KPI’s, and speaker program operations. The Director will serve as a key partner to cross-functional teams including Marketing, Medical Affairs, Regulatory, Legal, Compliance, and external vendors, driving operational excellence and enabling speed-to-market in a highly regulated and complex therapeutic landscape.

• Serve as a strategic partner to the bezuclastinib brand team, ensuring Marketing Operations aligns with Cogent Commercial objectives to enhance executional effectiveness.
• Develop and implement a marketing operations strategy aligned with the unique needs of bezuclastinib and its potential three indications.
• Drive continuous improvement in operational processes to support agility, scalability, and compliance.
• Lead budget planning, resource allocation, and vendor oversight to support commercial execution.
• Key commercial lead for the Cogent internal promotional review process (MLR) and manage the end-to-end content approval process for key commercial materials.
• Ensure timely and compliant review of promotional materials, including HCP and patient-facing assets.
• Manage critical systems supporting these processes such as Veeva Vault Promo Mats and ensure system optimization for content approval workflows.
• Work with marketing to ensure the execution of complex customer engagement plans into high-performing omnichannel campaigns across HCP, patient, and caregiver audiences.
• Collaborate with analytics teams to integrate insights into campaign design and optimization.
• Ensure systems and platforms readiness to track key data and metrics for campaign effectiveness and measurement.
• Ensure personalization and precision in outreach, leveraging data and…