Research Associate I​/II -O

Syst Immuneis a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).Syst Immunehas multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials.

Syst Immunehas a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

Syst Immune Inc . is seeking a motivated Research

AssociateI/II to join the Bioassay team within the Immuno-Oncology department.

This role will support the engineering of complex cell lines and the execution of cell-basedimmunoassays to enable the discovery and development of novel cancer therapeutics. The ideal candidate will be a strong experimentalist with direct experience in genetic modification (such as lentiviral transduction and knock-in/out) and bioassay execution who thrives in a fast-paced, collaborative environment.

This is a hands-on laboratory role focused on critical materials generation, assay execution, and data analysis. The successful candidate willmaintainhigh-quality experimental standards while developing deep technicalexpertisein immuno-oncology drug development.

This role is full-time onsite in Redmond, WA and will move to Bothell, WA fall 2026.

• Engineer stable cell lines using lentiviral transduction, CRISPR knock-ins, andknock-outs
• Analyze complex datasets, prepare technical reports, and present findings to internal teams.
• Perform rigorous batchqualificationof critical reagents and cell lines to ensure assay consistency.
• Maintain and manipulate complex co-cultures of primary immune cells and engineered cancer cell lines.
• Conduct functional assays using
  
  Incucytelive-cell imaging, flow cytometry, and ELISA-based platforms.
• Develop,optimize, andvalidatecell-based and immunoassays to support drug development programs.

• Research Associate I:
  • BS or MS in Biology, Immunology, Cell Biology,Bioengineering,Biochemistry, or related scientific field
  • Minimum 1+ year of industry laboratory experience (internships may be considered if highly relevant)
  • Hands-on experience with mammalian cell culture techniques and aseptic techniques
  • Experience with mammalian cell culture techniques
  • Exposure to genetic modification workflows such as transient transfections or lentiviral transduction
  • Basic familiarity executing immunoassays such as ELISA or flow cytometry
  • Strong organizational skills and attention to detail
  • Ability to work effectively in a team environment
• Research Associate II:
  • BS or MS in a relevant scientific discipline
  • Typically, 2–4 years of relevant industry experience
  • Direct experience engineering cell lines, including executing lentiviral transductions and knock-ins
  • Proven track record executing and troubleshooting cell-based assays and flow cytometry workflows
  • Demonstrated ability to work with moderate independence

• Experience supporting oncology, immuno-oncology, immunology, orbiologicsdrug discovery programs.
• Experience with single-cell cloning, CRISPR/Cas9 workflows, or stable cell lineselection.
• Proficiency with Incucytelive-cell imaging, multi-color flow cytometry, or MSD multiplex platforms.
• Exposure to high-throughput research settings or regulated laboratory environments.
• Strong data analysis software skills (e.g., Graph Pad Prism,Flow Jo) and scientific communication skills

The expected base salary range for this position is 60,000 - 80,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills. While most offers typically fall within the low to mid-pointof the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

Syst Immuneis a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

Syst Immune offers a comprehensive benefits package including: 100% paid employee premiums for…