Principal Research Associate, Analytical Development

Overview

The Role: Reporting to the Head of the Product Characterization group, the individual in this role will coordinate characterization and comparability studies to support advancement of Moderna’s pipeline, including commercial products. The incumbent should be familiar and have hands-on experience with most of the routine biochemical and biophysical characterization techniques used for RNA structural characterization, including mass spectrometry, spectroscopy, calorimetry, liquid chromatography, ELISA, light scattering and next generation sequencing.

Demonstrated writing skills are required for protocol drafting and report compilation. Polished communication skills are essential considering that the incumbent will regularly interact with other RAs and Scientists within the Analytical Development, Analytical Technical Operations and Process Development teams. The individual will present scientific findings/results internally or externally. The individual will also evaluate new technologies, optimize methods and write methods SOPs.

• Draft testing protocols and compile characterization reports in support of regulatory filings

• Coordinate sample generation and sample submissions for partner groups

• Execute testing for various characterization assays including calorimetry, spectroscopy, light scattering and next generation sequencing

• Perform data analysis and data trending utilizing good documentation practices

• Record and communicate findings, present results at internal or cross-functional meetings

• Write/Revise SOPs related to job function

• Collaborate with other members within the R&D departments throughout the company

• Perform general laboratory support activities including equipment maintenance and housekeeping

• Be accountable for project success and results delivery

• BS with at least 4 years of industry experience, or MS with at least 2 years of industry experience (Biophysics, Chromatography, Biochemistry, Molecular Biology, or related science)

• Experience in performing biophysical characterization with focus on mRNA structural characterization

• Experience with spectroscopy and calorimetry

• Excellent writing and documentation skills

• Excellent interpersonal and collaborative skills

• Ability to work independently and effectively in a highly dynamic environment

• This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

• At Moderna, we are focused on delivering on our mission by enabling talent to thrive. For this role, we are currently unable to offer immigration sponsorship. Candidates must already hold work authorization in US and be able to maintain that status without the need for future sponsorship.

• Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs

• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support

• Lifestyle Spending Accounts to personalize your well-being journey

• Family planning and adoption benefits

• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

• Savings and investment opportunities

• Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit…