Director, Assistant Controller

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Full Time Management Watertown, MA, US

Salary Range: $ To $ Annually

C4 Therapeutics (C4T) (Nasdaq: CCCC) is a clinical-stage biopharmaceutical company dedicated to delivering on the promise of targeted protein degradation science to create a new generation of medicines that transforms patients’ lives. C4T is progressing targeted oncology programs through clinical studies and leveraging its TORPEDO® platform to efficiently design and optimize small-molecule medicines to address difficult-to-treat diseases. C4T’s degrader medicines are designed to harness the body’s natural protein recycling system to rapidly degrade disease-causing proteins, offering the potential to overcome drug resistance, drug undruggable targets and improve patient outcomes.

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C4 Therapeutics is seeking an experienced Assistant Controller to join our Accounting & Finance team at a pivotal moment in our growth. Reporting to the Controller, this role will be a key technical and operational leader within Accounting, with ownership over the close process, internal controls, and several of C4T’s most complex accounting areas, including collaboration revenue, clinical trial accruals, and equity compensation.

This is a highly visible role for an accountant who enjoys both the technical rigor of public company accounting and the opportunity to build and mentor a growing team. As C4T advances its pipeline into Phase 3 clinical trials and begins commercial readiness activities, this individual will play an instrumental role in scaling the accounting function – including building out the team, implementing new systems, and furthering our automation and AI integration efforts.

• Manage the monthly, quarterly, and annual close process, ensuring accuracy, timeliness, and compliance with U.S. GAAP and public company reporting standards.
• Review balance sheet account reconciliations and supporting schedules prepared by the accounting team, ensuring completeness, accuracy, and timely resolution of open items.
• Own collaboration revenue accounting, including analysis of collaboration and license agreements under ASC 606, recognition of upfront, milestone, and royalty payments, and related disclosures.
• Oversee the Company’s equity compensation program and stock-based compensation accounting, including option, RSU, and ESPP activity, ASC 718 accounting, and common share/equity pool reconciliations.
• Own and manage the Company’s SOX internal control environment, including control design, execution, documentation, and remediation, partnering with internal and external auditors as needed.
• Play a key role in the preparation, review, and analysis of significant clinical trial accruals, partnering closely with Clinical Operations and CRO vendors to ensure accurate estimates and timely reporting.
• Serve as a mentor to and collaborate closely with other members of the Accounting team, fostering technical development, engagement, and a strong team culture.
• Work closely with the Controller and SVP, Finance & Accounting on financial reporting, forecasting, and cross-functional initiatives that support the broader Finance organization.
• Help build out the Accounting team as C4T advances into Phase 3 clinical trials and commercial readiness activities, including participating in hiring, onboarding, and development of new team members.
• Lead or support the implementation of new systems and process improvements, furthering the team’s automation and AI integration initiatives to increase efficiency and scalability.
• Partner with external…