Assistant​/Associate Professor in Biological Sciences

City: WEST LAFAYETTE

Intelligent Medicines – Structural Biology, Department of Biological Sciences, Purdue University

Position Description

As part of a transformative, university-wide initiative in One Health
- Intelligent Medicines
, the Purdue University Department of Biological Sciences invites applications for a full-time, tenure-track or tenured faculty position at the Assistant or Associate Professor level with a focus on Structural Biology for the development of next generation therapeutics. This position builds on the world-renowned legacy of innovation in structural and computational biology and biophysics at Purdue aiming to bridge next-generation structure determination with advanced computational workflows to accelerate molecular insights and therapeutic discovery.

We seek a forward-thinking, experimental researcher who integrates advanced physical and biophysical techniques with modern computational tools (including artificial intelligence and machine learning) to resolve impactful biological functions of complex macromolecular structures, dynamic assemblies, and cellular machinery.

We welcome candidates specializing in any of the following or related areas:

• Biomolecular Design & Therapeutics: Leveraging structure determination (e.g. via X-ray crystallography) and computational/AI workflows to design novel biologics, study drug-target interactions, or pioneer therapeutic innovations.
• Computational & Predictive Biochemistry: Developing or leveraging advanced tools for macromolecular modeling, biological image analysis , or AI-driven functional genomics .
• Next-Generation Structural Approaches: Pushing the boundaries of cryo-electron microscopy/tomography (cryo-EM/ET), in situ structural biology, or multi-modal scaling.

This strategicrecruitmentwillhelpadvance Purdue’s One Health initiative ( https://www.purdue.edu/onehealth/ ) which seeks to tackle complex challenges with real-world impact at the intersection of human, animal, and plant health. This recruitment initiative builds on previous strategic faculty recruitment initiatives in: (1) Integrated Health; (2) AI-Driven Biomolecular Design, and (3) Advanced Chemistry. In addition, a parallel strategic faculty recruitment initiative in Healthy and Resilient Living Systems is ongoing.

Through academic programs, research, facility infrastructure and industry partnerships, Purdue is making giant leaps in improving health outcomes for all living things and driving economic growth regionally and globally. This strategic faculty recruitment initiative focused on Intelligent Medicine sis expected to build on prior recruitment initiatives and existing Purdue research and academic strengths, to transform research and impact human, animal and environmental health by bridging silos and fostering collaboration across disciplines.

The Intelligent Medicines theme seeks to create a framework that improves human, animal, and environmental health through the integration of technology, data, and systems thinking. This faculty recruitment initiative is disease agnostic and aims to establish new capabilities in AI-enabled therapeutic development, non-animal models of disease, advanced manufacturing, intelligent health systems, digital twins, robotics, human factors, supply chain resilience, and health technology innovation.

By combining strengths in device innovation, computational intelligence, manufacturing systems, and healthcare operations, Purdue intends to create a highly visible flagship that strengthens industry engagement, expands workforce development opportunities, and attracts significant external funding.