Principal Clinical Scientist

What if your decades of clinical trial expertise could directly influence how AI reasons about medical evidence, regulatory data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the frontier of AI development — ensuring the clinical knowledge embedded in next-generation AI systems meets the highest standards of scientific and regulatory integrity.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work on their own schedule. No AI background required — your deep domain expertise is what matters.

• Organization:
  Alignerr
• Type:
  Hourly Contract
• Location:
  
  Remote
• Commitment: 10–40 hours/week

• Design and critically review clinical trial protocols used to generate high-quality, regulator-ready AI training datasets
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes
• Help establish quality standards for clinical evidence used in cutting-edge AI research workflows

• Senior-level clinical scientist with hands‑on experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail‑oriented — you hold clinical evidence to the highest standards
• Comfortable working independently and asynchronously in a remote environment

• Prior experience with data annotation, data quality review, or evaluation frameworks
• Background in clinical pharmacology, oncology, rare disease, or other specialized therapeutic areas
• Familiarity with AI tools or emerging applications of machine learning in clinical research

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert‑level work
• Collaborate with world‑leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch