Research Asst Genitourinary Medical Oncology – Research

Employer-paid medical coverage starting day one for employees working 30 hours/week, plus optional group dental, vision, life, AD&D, and disability insurance.

Accruals for PTO and Extended Illness Bank, plus paid holidays, wellness, childcare, and other leave options.

Tuition Assistance Program after six months of service and access to extensive wellness, fitness, and employee resource groups.

Defined-benefit pension through the Teachers Retirement System, voluntary retirement plans, and employer-paid life and reduced salary protection programs.

The employee will conduct and carry out research experiments and is required to discuss goals of projects with supervisors. Receives detailed verbal and/or written instructions on how to conduct an experiment in order to achieve the goals of the project. Verbally asks questions of supervisor and/or other laboratory personnel to clarify and obtain further information needed to prepare for and properly execute experiments.

Clear and concise verbal communication is important. The employee must possess good reading (English) and writing skills; some editing experience in scientific writing is desirable. Receives verbal and/or written instructions on the operation and maintenance of all laboratory equipment. Position will require periodic communications with vendors and other laboratory personnel to obtain technical information by talking on the telephone. Develops a step-by-step written procedure outlining the specific actions required to conduct the experiment before proceeding.

The successful candidate will exercise initiative and inventiveness in planning, executing and interpreting data obtained from experiments. Must be able to communicate results to principal investigators (PIs) and collaborators. Must have a well-developed esprit de corps and willingness to cooperate with all principals. Must have the ability to resolve, in consultation with PIs, various technical problems as they emerge that are related to experimental design and technique.

The position will require detailed, legible handwritten records of all experiments performed.

The employee will perform analysis of histopathological data, including IHC, IF and demultiplex-IF on human and mouse tissues. Candidates with skills in using Visiopharm and QuPath are highly preferred.

The employee will help with animal breeding, tagging, weaning, genotyping, tissue harvesting, as well as downstream processing and analysis. The employee will be responsible for animal care, organization of the colonies, xenograft and orthotopic tumor models, manipulation of the mice including tail vein/retro-orbital/intraperitoneal/subcutaneous injections, gavage treatments, tail vein bleeds, euthanasia, necropsy, and any additional animal related work.

Must be able to generate and analyze data for presentations and publications. Candidate with sound working knowledge and trouble shooting skills in some of the following techniques is preferred: immunohistochemistry, immunofluorescence staining, ELISA assays, western blot analysis, immunoprecipitation, gene knockdown/knockout, transfection/transduction of mammalian /bacterial cells, proliferation/apoptosis study, gene expression library construction, RT-PCR, gel electrophoresis of proteins and nucleic acids, mammalian cell culture, cryopreservation of cells, preparation of DNA, RNA, and protein from cells, blood, tissues, and FFPE slides for next-generation sequencing, microarray, methylation array, and protein array analyses.

Animal experiments including testing the efficacy and mechanisms of action of specific anti-cancer agents…