Senior Scientist II, R&D Bioinformatics

• Department:
  Analytics and Business Intelligence

ABOUT LGC BIOSEARCH TECHNOLOGIES:

With manufacturing sites across the US, UK, Germany and Denmark, LGC Biosearch Technologies has plans to continue growing. We deliver mission critical genomics to our diverse customer base in molecular diagnostics, pharma/biotech and agrigenomics. Our integrated portfolio of products, services and expertise supports our purpose of Science for a Safer World and we have embodied our mission by working with customers to enable research into life-altering treatment for disease and illness worldwide.

We are currently seeking candidates who are up for the challenge of operating in a high-growth, purpose-driven organisation.

The Senior Scientist II in R&D Bioinformatics contributes significantly to the growth of LGC’s molecular biology product portfolio. As a senior leader and subject matter expert, this person supports several R&D projects in the Diagnostics and Genomics business unit. The Senior Scientist II has extensive knowledge of the scientific principles in bioinformatics and genomics research and applies this expertise to invent and implement innovative experiments.

The main duty of this role is to foster innovation, compose and develop algorithms, tools, and pipelines for different PCR- and next generation sequencing (NGS)-based applications.

To perform this job successfully, an individual must be able to perform each of the following essential functions satisfactorily:

• Develop oligo building tools and pipelines for molecular techniques such as qPCR and NGS
• Develop algorithms and tools for NGS data analysis and new product creation
• Complete research projects in collaboration with multiple collaborators across the organization
• Provide algorithm and scientific mentorship to the internal and external software development teams
• Generate, optimize, and maintain scripts for routine genomic data processing, curation, and storage
• Provide customized data analysis support and training to wet-lab scientists as needed
• Build high-throughput multiplexing genotyping panels for human, plants, animals, and microbes
• Work together with Product Management, Project Management, Lab Services, and R&D teams on new product development and custom NGS projects/services
• Identify and define new product ideas or technologies, develop prototypes, conduct optimization studies, and present results to the leadership
• Attend meetings, conferences, symposia, and seminars to promote LGC capabilities and to keep abreast of scientific/technological developments
• Deliver high-quality product development documentation consistent with LGC’s quality systems

• Master or Ph.D. degree in a relevant field (bioinformatics, computer science, biostatistics, computational biology, genetics, biology)—or an equivalent combination of applicable education and work experience
• Minimum of 5 plus years of relevant work experience in a highly technical role with a focus in bioinformatics
• Proficiency in a high-level (e.g., Python,Perl) programming languages
• Demonstrated experience with Unix-based operating systems and bash shell scripting
• Strong expertise in crafting, building, and managing Docker-based environments
• Experience in software development including ticket management and version control (e.g., git)
• Experience in computational pipeline development and database management, as well as solid background in genomics and statistics
• Proven understanding of NGS algorithms and data analysis tools
• Practical experience in analyzing and handling extensive genomic datasets (e.g., whole genome sequencing, exome-seq, target enrichment, amplicon sequencing, RNA-seq, etc.)
• Practical experience with genome alignment,…