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Job Number:
Category: Research
Location: Worcester, MA
Shift: Day
Exempt/Non-Exempt: Exempt
Business Unit: UMass Chan Medical School
Department: School - Pathology - W821900
Job Type: Full-Time
Salary Grade: 86
Union Code: Non Union Position-W63-Residents/Post Docs
Num. Openings: 1
Post Date: May 8, 2025

An NIH-funded position is available in the laboratory of Dr. Kiera Clayton at the University of Massachusetts Chan Medical School for an exceptionally talented, motivated, and hardworking postdoctoral fellow to investigate the mechanisms of CD4+ T cell and macrophage resistance to killing by cytolytic immune cells.

Research projects include the identification of pathways that enhance macrophage survival following NK and CD8+ T cell attack (collaboration with Weill Cornell REACH Martin Delaney Collaboratory), assessing NK cell interactions with Mycobacterium tuberculosis-infected macrophages, and herpes virus-infected CD4+ T cells and macrophages. Experimental methods involve HIV, Mtb, and herpes virus infections with primary immune cells, cellular co-culture assays, flow cytometry and FACS analysis, RNA/CITE-Seq, CRISPR editing, and molecular cloning of mutant viruses.

The ideal candidate will have a PhD with lab experience in immunology, virology, and biochemistry, and experience in flow cytometry and working with human cells in BSL-2+ and BSL-3 settings. The successful candidate will join a vibrant research team exploring HIV, Mtb, and herpes virus immune evasion mechanisms to develop strategies for targeting chronic infections (https://(Use the "Apply for this Job" box below).).

The postdoctoral fellow will have an appointment at UMass Medical School and is encouraged to attend conferences, contribute to manuscript preparation, and engage in fellowship/grant writing. Salary will follow NIH and UMass guidelines. Candidates should send a statement of interest, future goals, and CV to Dr. Kiera Clayton yton. A minimum commitment of three years is required.

UMass Chan Medical School was recognized as a 2023 “DEI champion” by The Boston Globe and was named a U.S. News & World Report “2023 BEST MEDICAL GRAD SCHOOL” for Primary Care and Research.