Biologist II

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Target PR Range: $37-47/hr

The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated and energetic bioanalytical scientist to join the biologics bioanalysis, characterization and proteomics (BBCP) group. The primary responsibility of this position is to support LC‑MS‑based bioanalysis and method development for biologic entities such as monoclonal antibodies, multi‑specific antibodies, antibody‑drug conjugates (ADCs), and other novel modalities. The successful candidate will have experience in optimizing and implementing hybrid LC‑MS‑based bioanalytical methods to support non‑regulated preclinical PK and TK studies.

Responsibilities include routine sample preparation, method development, instrument maintenance, data analysis, report writing, and presenting data at internal and external meetings.

• Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody‑siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems.
• Operate and maintain LC/MS instruments to generate high‑quality experimental data.
• Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements.
• Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
• Communicate data interpretation internally and externally.

• Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
• Highly motivated, self‑driven and results‑oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
• Hands‑on experience with QQQ (SCIEX) is required; additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
• Hands‑on experience with biologics bioanalysis is highly desired; additional experience with oligonucleotide analysis is a plus.
• Hands‑on experience with immuno‑affinity purification and automation systems (e.g., TECAN, Assay Map Bravo or Hamilton) is highly desired.
• In‑depth understanding of PK, TK and PK/PD studies is preferred.

• Seniority level:
  Not Applicable
• Employment type:
  
  Full‑time
• Job function:
  Research, Analyst, and Information Technology

The Planet Group of Companies is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.