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Biologist II

Job in Worcester, Worcester County, Massachusetts, 01609, USA
Listing for: Mindlance
Full Time position
Listed on 2026-01-04
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research
Job Description & How to Apply Below

Responsibilities

  • Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody‑siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems.
  • Operate and maintain LC/MS instruments to generate high‑quality experimental data.
  • Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements.
  • Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
  • Communicate data interpretation internally and externally.
Qualifications
  • Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired.
  • Highly motivated, self‑driven and results‑oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
  • Hands‑on experience with QQQ (SCIEX) is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus.
  • Hands‑on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus.
  • Hands‑on experience with immuno‑affinity purification and automation systems (e.g., TECAN, Assay Map Bravo or Hamilton) is highly desired.
  • In‑depth understanding of PK, TK and PK/PD studies is preferred.

EEO:‑ Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans

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