Associate Director, Sourcing Strategy & Procurement

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Associate Director, Strategic Sourcing will lead strategic sourcing initiatives and category management activities supporting Chemistry, Manufacturing & Controls (CMC), Supply Chain, and Quality Assurance (QA) functions. This role is responsible for developing and executing sourcing strategies, managing supplier relationships, negotiating contracts, driving value creation, mitigating supply risk, and ensuring alignment with business objectives in a dynamic and highly regulated biopharmaceutical environment.

The successful candidate will partner closely with Technical Operations, Manufacturing, Quality, Regulatory, Supply Chain, Finance, Legal, and other stakeholders to support clinical and commercial programs while ensuring continuity of supply, quality compliance, and cost optimization.

• Develop and execute category strategies for CMC, Supply Chain, and Quality-related spend categories, including but not limited to:
  • Contract Development and Manufacturing Organizations (CDMOs)
  • Support analytical and CMC activities
  • Raw materials, APIs, excipients, and packaging components
  • Logistics, transportation and warehousing services
  • Quality and compliance consulting services
• Conduct market assessments, supplier evaluations, and benchmarking to identify opportunities for cost savings, innovation, risk mitigation, and operational efficiency.
• Lead competitive sourcing events including RFIs, RFPs, RFQs, supplier selection, and contract negotiations.

• Build and maintain strategic relationships with key suppliers and service providers.
• Establish supplier performance metrics and governance frameworks to monitor quality, delivery, service, innovation, and compliance.
• Facilitate regular business reviews with critical suppliers.
• Help define and track KPIs that measure sourcing and procurement performance, supplier reliability, regulatory/SOP adherence, and value creation across scientific and non-scientific categories.
• Collaborate with business stakeholders to resolve supplier performance issues and drive continuous improvement initiatives.

• Lead complex commercial negotiations, including Master Service Agreements, Quality Agreements, Supply Agreements, Statements of Work, and pricing arrangements.
• Partner with Legal, Quality, Finance and business stakeholders to ensure contractual terms appropriately address risk, compliance, quality, intellectual property, and business requirements.
• Drive favorable commercial outcomes while maintaining strong supplier partnerships.

• Serve as a trusted advisor to CMC, Supply Chain, and Quality leadership teams.
• Support strategic initiatives including clinical and commercial product launches, technology transfers, manufacturing scale-up activities, and network optimization efforts.
• Collaborate with stakeholders to forecast sourcing needs and align procurement strategies with organizational priorities.

• Identify and proactively mitigate supply chain, quality,…