PhD Position: Synthetic Chemistry Lipid Nanoparticle- Imaging Probes

PhD Position:
Synthetic Chemistry for Lipid Nanoparticle-based Imaging Probes

ETH Zürich is well known for its excellent education, ground‑breaking fundamental research and for implementing its results directly into practice.

We are looking for a PhD candidate to join our group in the Department of Chemistry and Applied Biosciences to work on the design and synthesis of imaging probes to functionalize lipid nanoparticles. Our group has diverse knowledge in various topics including organic synthesis, imaging, and nanotechnology, and our strength lies in the synthesis of organic molecules for diverse applications in the field of bio‑ and nano‑technology.

For this position, a project on the synthesis of imaging probes, targeting peptides and therapeutic molecules and covalent functionalization of the surface of lipid nanoparticles for various applications is envisaged.

Research Topics within Our Group:

• MRI and NIR probe for in vivo and in vitro imaging of diseases
• Chemical force spectroscopy and nanolithography by chemically functionalized AFM tip
• Fullerene‑based biomaterials
• Supramolecular complexation and self‑assembly

You can find out more about our group on our website.

• Organic synthesis
• Structural characterization of organic molecules
• Lipid nanoparticle synthesis and characterization
• Various imaging applications
• Collaboration within our group and with other researchers
• Group responsibilities
• Teaching – practical labs or lecture courses

The ideal candidate will have a strong background in preparative synthetic organic chemistry. Experience with soft materials, photochemistry, imaging, and peptide chemistry are welcome but not essential.

• A highly‑motivated student who has completed a Master’s degree in chemistry or a similar field
• Able to work independently on your own project but also collaboratively with other scientists
• Solid background in organic synthesis
• High proficiency in oral and written English
• Preferred prior experience with nanoparticles and characterization, though not an essential requirement

• Access to ETH facilities for synthesis, characterization, and microscopy
• Interesting projects with opportunities for independent exploration
• Ability to broaden your knowledge through ETH courses in chemistry and related sciences

We look forward to receiving your online application with the following documents:

• CV
• Master’s diploma/certificate

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Questions regarding the position should be directed to Prof. Dr. Yoko Yamakoshi z.ch (no applications).

Title

PhD Position:
Synthetic Chemistry for Lipid Nanoparticle‑based Imaging Probes