PhD Position: Synthetic Chemistry Lipid Nanoparticle- Imaging Probes

PhD Position:
Synthetic Chemistry for Lipid Nanoparticle-based Imaging Probes 100%, Zurich, fixed-term

We are looking for a PhD candidate to join our group in the Department of Chemistry and Applied Biosciences to work on the design and synthesis of imaging probes to functionalize lipid nanoparticles. Our group has diverse knowledge in various topics including organic synthesis, imaging, and nanotechnology and our strength lies in the synthesis of organic molecules for diverse applications in the field of bio‑ and nano‑technology.

For this position, a project on the synthesis of imaging probes, targeting peptides and therapeutic molecules and covalent functionalization of the surface of lipid nanoparticles for various applications is envisioned.

Research Topics within Our Group:

• MRI and NIR probe for in vivo and in vitro imaging of diseases
• Chemical force spectroscopy and nanolithography by chemically functionalized AFM Tip
• Fullerene-based biomaterials
• Supramolecular complexation and self‑assembly

You can find out more about our group on our website.

• Organic synthesis
• Structural characterization of organic molecules
• Lipid nanoparticle synthesis and characterization
• Various imaging applications
• Collaboration within our group and with other researchers
• Group responsibilities
• Teaching - practical labs or lecture courses

The ideal candidate will have a strong background in preparative synthetic organic chemistry. Experience with soft materials, photochemistry, imaging, and peptide chemistry are welcome but not essential.

• A highly‑motivated student who has completed a Master's degree in chemistry or a similar field
• Able to work independently on your own project but also collaboratively with other scientists
• Solid background in organic synthesis
• High proficiency in oral and written English
• Preferred prior experience with nanoparticles and characterization, though not an essential requirement

• Access to ETH facilities for synthesis, characterization, and microscopy
• Interesting projects with opportunities for independent exploration
• Ability to broaden your knowledge through ETH courses in chemistry and related sciences
• Lovely group members and colleagues

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Sustainability is a core value for us – we are consistently working towards a climate‑neutral future.

We look forward to receiving your online application with the following documents:

• Motivation letter
• CV
• Master's diploma/certificate

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Further information about the Department of Chemistry and Applied Biosciences can be found on our website. Questions regarding the position should be directed to Prof. Dr. Yoko Yamakoshi z.ch (no applications).

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting‑edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.