Scientist​/Senior Scientist

Job Description Roles & Responsibilities

• Lead in vitro assay development
• Identify and investigate PD biomarkers relevant to disease and drug intervention
• Develop & design experiments and research plans to elucidate therapeutic mechanism of action
• Conduct and troubleshoot a wide range of biological/molecular/biochemical assays including, but not limited to: FACS, ELISAs, RT-PCR, Western blotting, co-IPs
• Manage/participate in CRO relationships
• Mentoring of junior colleagues
• Document, analyze, interpret and present experimental data in a clear and concise manner, contributing to data room and investor presentations
• Independently research new technologies and approaches to apply to the drug discovery and development pipeline
• Present in high level conferences, draft and submit manuscripts, contribute to grant writing

• Setting up the lab and best practices
• Plan and Design experiments coordinating with clear milestones on the project
• Perform validation assays and preclinical experiments
• Perform data analysis and prepare and present reports
• Drive CRO interaction and vendor management for preclinical studies
• Organize laboratory, develop SOPs, maintain equipment, order supplies, maintain detailed records of laboratory experiments, and other duties as required

• PhD with 3-8 years of recent lab-based biotech/pharma industry experience
• Experience with human (and mouse) biomarkers
• Experience with protein assay platforms (ELISA, Luminex, MSD, etc.)
• Experience with flow cytometry methods and interpretation (immunophenotyping, cell markers)
• Experience and ability to plan and execute molecular, cellular and biochemical techniques in 96/ well format
• Able to take direction but also work independently and troubleshoot
• Demonstrates attention to detail and record keeping
• Team player: understands and appreciates working towards common goals in start-up environment and in a small team
• Flexibility to adapt workplans to rapidly changing priorities and deadlines
• Candidates must possess a valid work permit in Switzerland

• Background in fibrosis, immunology/inflammation, cytokines, growth factors, extracellular matrix biology
• Knowledge/experience working with biotherapeutics, mix modalities
• Experience with phenotypic assay development (flow cytometry and microscopy)
• Experience in high throughput screening such as by phenotype, microscopy, ELISA
• Experience with IHC

• Company mission that aims to impact the lives of patients with life threatening conditions with a novel & innovative approach
• An opportunity to work in the exciting field of mechno-medicine and its broad implications in fibrosis & oncology
• Fast-paced, highly stimulating environment with a collaborative atmosphere
• Unique opportunity to join a company at an early stage, with avenues for career development
• Competitive salary, with additional advantages and incentives including a fully-funded pension
• Respectful and equal opportunity work environment, in a world-class location

TANDEM strives to build a diverse team, and particularly encourages women and other groups underrepresented in the Biotech/Bioengineering field to apply.