Postdoc in Intravital Microscopy

We are seeking a highly motivated postdoctoral researcher to join our group at the Department of Biology, ETH Zurich. The successful candidate will use state-of-the-art intravital microscopy to study macrophage biology and tissue repair in vivo.

Our lab investigates how tissue-resident immune cells, particularly macrophages, contribute to tissue homeostasis and repair, with a focus on the mesothelium, serosal cavities, and the liver. Using intravital imaging, we track cell behavior and dynamics in real time within living tissue, linking cellular mechanisms to organ-level repair processes. The project has a strong translational angle, motivated by clinical challenges in abdominal surgery such as adhesion formation, and is conducted in close collaboration with clinicians to bridge basic mechanistic insight with surgical practice.

• Design and perform intravital microscopy experiments in mouse models
• Extend intravital imaging approaches to additional organs
• Investigate macrophage dynamics and/or serosal repair mechanisms
• Analyze imaging data using quantitative and computational approaches
• Perform spectral flow cytometry and standard bioinformatics analysis of single-cell and spatial transcriptomics data, correlating findings with imaging data
• Present findings at lab meetings and international conferences
• Contribute to manuscript preparation and grant writing
• Co-supervise MSc/PhD students

• PhD in Immunology, Cell Biology, or a related field
• Prior experience with rodent models required
• An interest in tissue repair or regenerative biology is a plus
• Hands-on experience with intravital/in vivo imaging is an advantage
• Strong quantitative and image-analysis skills are an advantage
• Solid R and/or Python skills, ideally paired with modern AI-assisted coding workflows (e.g., "Claude Code"), are a clear advantage
• Track record of first-author publications
• Excellent written and spoken English; team-oriented mindset

• A newly established lab with cutting-edge fluorescent reporter models ready to be characterized
• A vibrant, founder-like atmosphere as an early member of a young, growing team
• Access to cutting-edge intravital imaging infrastructure
• A lab at the forefront of AI adoption in research, with access to high-end computational resources and environments — bring your own tricks
• Mentoring and career development support
• Initial 1-year contract with annual renewal; funding for the position is secured for up to 4 years.

Working, teaching and research at ETH Zurich

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